Skip to main content

Table 3 Perioperative Cytokine Concentrations

From: Effects of anesthetic depth on perioperative T lymphocyte subsets in patients undergoing laparoscopic colorectal cancer surgery: a prospective, parallel-controlled randomized trial

 

BIS 35 (n = 30)

BIS 55 (n = 30)

Difference (95% CI)

P Value

IL-6, pg/ml

    

 T0

2.3 (2.2–2.6)

2.7 (2.2-3.0)

-0.2 (-0.5 to 0.1)

0.181

 T1

2.5 (2.2-3.0)

2.7(2.2-3.0)

-0.1 (-0.4 to 0.3)

0.745

 T2

2.6 (2.2-3.0)

3.4 (2.9–3.8)

-0.7 (-1.1 to -0.3)

0.001

 T3

2.7 (2.2–3.3)

3.0 (2.7–3.7)

-0.4 (-0.8 to 0.1)

0.085

VEGF-α, pg/ml

    

 T0

4.8 (4.0-6.2)

5.7 (4.2–7.8)

-0.7 (-1.9 to 0.3)

0.178

 T1

5.3 (4.3–7.8)

6.4 (4.7–7.4)

-0.4 (-1.7 to 0.9)

0.511

 T2

5.4 (4.9–7.3)

6.8 (5.2–8.8)

-1.0 (-2.3 to 0.1)

0.070

 T3

5.8 (5.4-8.0)

7.0 (5.6–8.5)

-0.9 (-2.2 to 0.1)

0.115

IFN-É£, pg/ml

    

 T0

4.9 (4.1–5.8)

5.3 (3.9–7.1)

-0.3 (-1.4 to 0.8)

0.589

 T1

5.3 (3.6–8.7)

5.0 (3.3–6.9)

0.8 (-0.8 to 2.1)

0.383

 T2

5.9 (4.0-6.1)

6.1 (4.3–7.9)

-0.9 (-1.9 to 0.3)

0.249

 T3

5.0 (3.6–6.7)

5.0 (3.7–5.7)

0.3 (-0.7 to 1.4)

0.559

  1. Data are expressed as median (interquartile range) or mean ± SD with difference (95% CI).
  2. T0: Preoperative, T1: Immediately after operation, T2: 24 h after operation, T3: 5 days after operation
  3. IL = Interleukin; VEGF = Vascular Endothelial Growth Factor; IFN = Interferon.