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Table 5 Comparison of primary and secondary outcomes within 48 h postoperatively after inverse probability of treatment weighting

From: Use of sugammadex is associated with reduced incidence and severity of postoperative nausea and vomiting in adult patients with obesity undergoing laparoscopic bariatric surgery: a post-hoc analysis

Outcomes

0–24 h after surgery

 

24–48 h after surgery

OR/MDa

(95% CI)

P value

 

OR/MDa

(95% CI)

P value

PONV

0.53 (0.48–0.60)

< 0.001b

 

0.82 (0.74–0.91)

< 0.001b

Severity of PONV

0.25 (0.19–0.34)

< 0.001b

 

0.72 (0.58–0.90)

0.004b

PON

0.77 (0.67–0.88)

< 0.001b

 

0.89 (0.83–0.96)

0.004b

Severity of PON

0.58 (0.43–0.77)

< 0.001b

 

0.89 (0.83–0.97)

0.005b

POV

0.60 (0.53–0.68)

< 0.001b

 

0.91 (0.84–0.99)

0.022b

Severity of POV

0.30 (0.22–0.41)

< 0.001b

 

0.84 (0.69–1.03)

0.087

Rescue antiemetic therapy

0.70 (0.62–0.80)

< 0.001b

 

0.94 (0.88–1.01)

0.087

Water intake

170.5

(108.5–287.2)

< 0.001b

 

249.0

(115.2–420.4)

< 0.001b

  1. Abbreviations: CI confidence interval, MD mean difference, N/A not applicable, OR odds ratio, PONV postoperative nausea and vomiting, PON postoperative nausea, POV postoperative vomiting
  2. a Effect size: OR for PONV, PON, POV and rescue antiemetic therapy, and MD for water intake
  3. b Statistically significant (P < 0.05)