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Table 4 Individual effect of OPRM1 A118G on VAS of PACU

From: Is OPRM1 genotype a valuable predictor of VAS in patients undergoing laparoscopic radical resection of colorectal cancer with fentanyl?

Exposure

Non-adjusted

Adjust model I

Adjust model II

OR(95%CI)

P Value

OR(95%CI)

P Value

OR(95%CI)

P Value

OPRM1 A118G

 GG

1.0

 

1.0

 

1.0

 

 GA + AA

14.73 (3.21, 67.49)

0.001

16.55 (3.01, 91.15)

0.001

19.94 (3.14, 126.82)

0.002

  1. Adjustment model I: adjusted according to age, sex, weight, height, and operation duration
  2. Adjustment model II: adjusted according to age, sex, weight, height, operation duration and the polymorphisms of CYP3A4 *1G、CYP3A5 *3 and COMT Val158Met polymorphisms
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BMC Anesthesiology

ISSN: 1471-2253

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