Table 2 Characteristics of subjects in the research
Characteristic | VAS < 4 | VAS ≥ 4 |
|---|---|---|
NO of paticipants | 92 | 9 |
Age | 59.53 ± 5.87 | 61.67 ± 4.00 |
Gender | ||
Male | 53 (57.61%) | 5 (55.56%) |
Female | 39 (42.39%) | 4 (44.44%) |
Weight | 62.23 ± 9.17 | 64.22 ± 7.60 |
Height | 164.80 ± 7.77 | 162.89 ± 6.53 |
Dosage of fentanyl | 8.95 ± 2.02 | 10.21 ± 2.28 |
Operation time | 2.33 ± 0.54 | 2.26 ± 0.33 |
CYP3A4 *1G | ||
*1/*1 | 47 (51.09%) | 3 (33.33%) |
*1/*1G + *1G/*1G | 45 (48.91%) | 6 (66.67%) |
OPRM1 A118G | ||
GG | 81 (88.04%) | 4 (44.44%) |
GA + AA | 11 (11.96%) | 5 (55.56%) |
COMT Val158Met | ||
GG | 48 (52.17%) | 5 (55.56%) |
GA + AA | 44 (47.83%) | 4 (44.44%) |
CYP3A5 *3 | ||
GG | 43 (46.74%) | 2 (22.22%) |
GA + AA | 49 (53.26%) | 7 (77.78%) |