Table 1 Characteristics of the included studies
Study | Year | Study design | Participants | Sample Size | Intervention Drug | Intervention Drug Dosage | Duration | Side Effects |
|---|---|---|---|---|---|---|---|---|
Saverio Dragoni | 2007 | R,DB,PC | Healthy population | 28 | GTN, PETN | GTN1.2 mg 2 h; PETN80 mg/d | 24 h | Not reported |
Tommaso Gori | 2007 | R,DB,PC | Healthy non-smokers males | 17 | GTN | 0.6 mg/h, 2 h/day | 24 h | Not reported |
Andrew J. Webb | 2008 | R,SB,PC | Healthy population | 10 | Beetroot juice | 500 ml | 2 h | Not reported |
Thomas E | 2013 | R,SB,PC | Healthy population | 10 | Nitrite | 1 μmol/ml,1.5 ml/min for 20 min | pre, post 20 min | Not reported |
Kelsey McLaughlin | 2014 | R,SB,PC | Healthy population | 34 | GTN | 0.6 mg/h, 2 h/day | 24 h, 7 day | Not reported |
Y.B. Somani | 2022 | R,SB,PC | Early postmenopausal women | 11 | Beetroot juice | 140 ml,about nitric acid 9.7 mmol | pre 100 min | Not reported |
Monica Lisi | 2012 | R,SB,PC | Healthy population | 20 | GTN, PETN | GTN0.6 mg/h, 2 h/day; PETN80 mg/d | pre 7 day | Not reported |