Comparison of the recovery profile of remimazolam with flumazenil and propofol anesthesia for open thyroidectomy

BMC Anesthesiology

Table 3 Comparison of the postoperative outcomes between the remimazolam-based and propofol-based total intravenous anesthesia

Characteristics	Remimazolam group (n = 28)	Propofol group (n = 29)	Mean or median or risk difference^a (95% Confidence interval)	P-value
In the PACU
Initial modified Aldrete score	7 (7–8)	7 (7–7)	0 (0–1)	0.063
Rescue analgesics during the PACU stay	5 (17.9)	8 (27.6)	-0.10 (-0.31–0.12)	0.377
PONV during the PACU stay	0	0
Length of PACU stay, min	30 (30–34.5)	30 (30–39)	0 (-2–2)	0.653
In the ward
Rescue analgesics during the first 24 h Postoperatively	12 (42.9)	11 (37.9)	0.05 (-0.21–0.30)	0.704
PONV during the first 24 h Postoperatively	3 (10.7)	0	0.11 (-0.01–0.22)	0.067
QoR-15 K score at 24 h postoperatively	125 (110–135)	129 (110–139)	-2 (-10–6)	0.571
Length of hospital stay, days	4 (4–5)	4 (4–5)	0 (0–0)	0.377

Values are median (IQR) or number (proportion)
^a Median or risk differences are expressed as the remimazolam group versus the propofol group. PACU post-anesthesia care unit, PONV postoperative nausea and vomiting, QoR-15 K Korean version of the quality of recovery-15

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