Table 2 Comparison of the intraoperative outcomes between the remimazolam-based and propofol-based total intravenous anesthesia
Characteristics | Remimazolam group (n = 28) | Propofol group (n = 29) | Mean or median or risk differencea (95% Confidence interval) | P-value |
|---|---|---|---|---|
Intraoperative mean blood pressure | ||||
MDPE, % | 7.2 (12.7) | -4.1 (11.5) | 11.3 (4.7–18.0) | 0.005 |
MDAPE, % | 9.4 (7.6–16.2) | 11.7 (8.3–14.9) | -0.3 (-3.1–2.9) | 0.894 |
Wobble, % | 5.6 (4.6–7.5) | 5.9 (4.9–8.0) | -0.5 (-1.9–0.8) | 0.412 |
Intraoperative vasopressor | 7 (25.0) | 13 (44.8) | -0.20 (-0.44–0.04) | 0.109 |
Intraoperative BIS value | ||||
MDPE, % | 4.3 (9.8) | -12.9 (11.8) | 17.3 (11.4–23.1) | < 0.001 |
MDAPE, % | 12.0 (8.3–14.0) | 16.0 (12.0–22.0) | -4 (-8.0–-2.0) | 0.002 |
Wobble, % | 8.0 (4.5–10.0) | 10.0 (8.0–13.0) | -3.0 (-5.0–-2.0) | 0.001 |
BIS value at the end of surgery | 57.7 (3.8) | 52.3 (5.0) | 5.5 (3.0–7.9) | < 0.001 |