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Table 4 Pre and post-operative P300 latency and amplitude, in patients in Nitroglycerine and Phentolamine groups

From: Comparative effect of deliberate hypotensive anesthesia using nitroglycerine vs. phentolamine on event related potentials and cognitive functions in patients undergoing septoplasty: a randomized controlled trial

P300

Preoperative assessment

[Median (IQR)]

Postoperative assessment

[Median (IQR)]

P- value

P- value between groups

Latency

Nitroglycerine group

322.7 (288.52- 344.86)

476.035 (430.135- 575.088)

< 0.001*

0.003*

Phentolamine group

321.86 (309.53- 346.76)

413.77 (363.065–471.63)

< 0.001*

Amplitude

Nitroglycerine group

4.47 (2.98–6.41)

1.93 (1.22–2.76)

< 0.001*

0.099

Phentolamine group

3.7 (2.4–4.5)

1.28 (1.01–2.145)

< 0.001*

  1. Values are expressed as median (Q1-Q3)
  2. Wilcoxon test was used for comparison between pre and post-operative quantitative variables, Mixed ANOVA test was used for comparing pre and post-operative quantitative variables in the two groups,
  3. *P-value ≤ 0.05 is considered significant