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Table 1 Baseline characteristics of study participants

From: Efficacy and safety of remimazolam tosilate versus propofol in patients undergoing day surgery: a prospective randomized controlled trial

Variables

RT

(n = 38)

RT + flumazenil

(n = 38)

Propofol

(n = 38)

P value

Age (y)

    

 Mean ± SD

43.5 ± 15.6

44.7 ± 16.8

44.3 ± 18.1

0.951

 ≥ 65

6(15.8)

7(18.4)

7(18.4)

0.941

Male

14(36.8)

22(57.9)

19(50.0)

0.179

Weight (kg)

63.6 ± 12.6

66.6 ± 11.3

65.9 ± 13.5

0.540

Height (cm)

166.7 ± 8.6

168.7 ± 7.8

168.1 ± 9.1

0.568

BMI (kg/m2)

22.7 ± 3.4

23.3 ± 3.3

23.2 ± 3.7

0.729

ASA physical status

   

0.868

 I

17(44.7)

17(44.7)

19(50.0)

 

 II

21(55.3)

21(55.3)

19(50.0)

 

Comorbid medical conditions

    

 Hypertension

10(26.3)

10(26.3)

5(13.2)

0.278

 Diabetes

5(13.2)

1(2.6)

2(5.3)

0.270

 Coronary heart disease

1(2.6)

0(0.0)

1(2.6)

1.000

 Thyroid disease

3(7.9)

1(2.6)

2(5.3)

0.870

 Arrhythmia

4(10.5)

4(10.5)

4(10.5)

1.000

Surgery type

   

0.112

 Urology

14(36.8)

24(63.2)

20(52.6)

 

 Obstetrics and Gynecology

16(42.1)

8(21.1)

7(18.4)

 

 General surgery

7(18.4)

6(15.8)

10(26.3)

 

 Thoracic surgery

1(2.6)

0(0.0)

1(2.6)

 

Preoperative laboratory tests

    

 Neutrophil / lymphocyte ratio, %

2.07(1.57–2.68)

2.26(1.81–3.52)

2.28(1.76-3)

0.212

 Platelet / lymphocyte ratio, %

115.47(106.40-147.97)

133.93(109.89-165.58)

138.99(105.92-164.67)

0.371

 ALT (U/L)

13.50 (9.00-20.25)

14.00 (12.00-18.25)

15.00 (10.00-22.75)

0.663

 Urea (mmol/L)

4.80 (4.20–6.25)

5.35 (4.38–6.62)

4.80 (4.23–5.38)

0.269

 TBIL (µmol/L)

8.55 (5.78–12.28)

10.80 (8.90–12.80)

10.05 (7.62–12.47)

0.222

 Duration of surgery (min)

42.2 ± 27.7

38.6 ± 29.1

38.7 ± 25.1

0.767

  1. Data are presented as mean ± SD, numbers (percentages) or median [IQR], as appropriate
  2. Abbreviations: ASA, American Society of Anesthesiologists; BMI, body mass index; RT, remimazolam tosilate; SD, standard deviation; ALT, alanine aminotransferase; TBIL, total bilirubin