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Table 3 Comparison of primary and secondary outcomes within the first 24 h and 24–48 h postoperatively between the two groups

From: Penehyclidine hydrochloride for treating postoperative nausea and vomiting after laparoscopic bariatric surgery: a double-blinded randomized controlled trial

Variable

0–24 h after surgery

P-value

24–48 h after surgery

P-value

Control

group

(n = 113)

PHC

group

(n = 221)

Control

group

(n = 113)

PHC

group

(n = 221)

PONV

58 (51)

101 (46)

0.330

16 (14)

24 (11)

0.385

Severity of PONV

      

 I

55 (49)

120 (54)

0.481

97 (86)

197 (89)

0.147

 II

12 (11)

22 (10)

11 (10)

14 (6)

 III

21 (19)

45 (20)

2 (2)

9 (4)

 IV

25 (22)

34 (15)

3 (3)

1 (1)

PON

12 (11)

22 (10)

0.850

11 (10)

14 (6)

0.273

Severity of PON

      

 I

5 (4)

6 (3)

0.051

4 (4)

6 (3)

0.236

 II

7 (6)

10 (5)

7 (6)

6 (3)

 III

0 (0)

6 (3)

0 (0)

2 (1)

POV

46 (41)

79 (36)

0.377

5 (4)

10 (5)

0.967

Severity of POV

      

 I

67 (59)

142 (64)

0.489

108 (96)

211 (96)

0.133

 II

6 (5)

15 (7)

2 (2)

6 (3)

 III

15 (13)

30 (14)

0 (0)

3 (1)

 IV

25 (22)

34 (15)

3 (3)

1 (1)

Rescue antiemetic therapy

30 (27)

49 (22)

0.376

3 (3)

5 (2)

0.826

Water intake (ml)

450 ± 160

459 ± 158

0.628

1195 ± 380

1112 ± 390

0.065

  1. Categorical data are presented as n (%), and continuous data are presented as mean ± standard deviation
  2. Abbreviations: PHC penehyclidine hydrochloride, PONV postoperative nausea and vomiting, PON postoperative nausea, POV postoperative vomiting