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Table 1 Baseline demographics and intraoperative variables

From: Penehyclidine hydrochloride for treating postoperative nausea and vomiting after laparoscopic bariatric surgery: a double-blinded randomized controlled trial

Variable

Control group

(n = 113)

PHC group

(n = 221)

P-value

Age (years)

34 ± 9

33 ± 8

0.347

Sex (Male)

25 (22)

68 (31)

0.091

Height (cm)

168 ± 8

168 ± 8

0.909

Weight (kg)

108 ± 25

107 ± 23

0.503

BMI (kg/m2)

38 ± 7

38 ± 7

0.391

ASA physical status

   

 II

49 (43)

103 (47)

0.573

 III

64 (57)

118 (53)

Apfel risk score

   

 0

2 (2)

12 (5)

0.126

 1

13 (11)

39 (18)

 2

48 (42)

97 (44)

 3

46 (41)

67 (30)

 4

4 (4)

6 (3)

Comorbidities

   

 Diabetes mellitus

42 (37)

84 (38)

0.881

 Hypertension

22 (20)

43 (20)

0.998

Smoking

17 (15)

46 (21)

0.196

History of motion sickness

3 (3)

6 (3)

0.974

Types of surgery

   

 LSG

70 (62)

134 (61)

0.904

 LSG-JJB

28 (25)

55 (25)

 LSG-DJB

10 (9)

18 (8)

OAGB

5 (4)

14 (6)

Duration of the anesthesia (min)

93 ± 22

92 ± 23

0.619

Duration of the operation (min)

77 ± 22

76 ± 22

0.867

IOC (mg)

56.8 ± 6.9

58.2 ± 7.5

0.103

Sugammadex

34 (30)

61 (28)

0.635

Neostigmine

79 (70)

160 (72)

0.635

Fluid infusion (ml)

1369 ± 341

1402 ± 370

0.433

Fluid output (ml)

203 ± 67

191 ± 83

0.183

Duration of mechanical ventilation (min)

120 ± 28

120 ± 27

0.768

Duration of PACU stay (min)

66 ± 27

66 ± 23

0.968

Rescue opioids

75 (66)

124 (56)

0.071

  1. Categorical data are presented as n (%), and continuous data are presented as mean ± standard deviation
  2. Abbreviations: ASA American Society of Anesthesiologists, BMI body mass index, IOC intraoperative opioids consumption (as intravenous morphine equivalent), LSG laparoscopic sleeve gastrectomy, LSG-DJB laparoscopic sleeve gastrectomy plus duodenojejunal bypass, LSG-JJB laparoscopic sleeve gastrectomy plus jejunojejunal bypass, OAGB one anastomosis gastric bypass, PACU postanesthesia care unit, PHC penehyclidine hydrochloride