Association of estimated glomerular filtration rate and all-cause mortality in acute pancreatitis: a retrospective analysis

Table 2 Relationship between eGFR and 28-day mortality in different Cox proportional hazards regression models

Exposure	Crude Model		Model I		Model II
Exposure	HR (95%CI)	P-value	HR (95%CI)	P-value	HR (95%CI)	P-value
eGFR per increase 10 ml/min/1.73m²	0.80 (0.73, 0.86)	< 0.0001	0.82 (0.75, 0.90)	< 0.0001	0.85 (0.76, 0.96)	0.008
eGFR groups
≥ 90	Ref		Ref		Ref
60–90	2.58 (0.79, 8.37)	0.115	1.78 (0.54, 5.87)	0.345	2.16 (0.64, 7.23)	0.214
30–60	4.70 (1.60, 13.81)	0.005	2.66 (0.86, 8.21)	0.088	2.60 (0.82, 8.21)	0.104
< 30	9.13 (3.19, 26.10)	< 0.0001	5.82 (1.96, 17.26)	0.002	4.96 (1.41, 17.36)	0.012
P for trend		< 0.0001		< 0.0001		0.010

Crude Model: Adjusted none
Model I: Adjusted for gender; age
Model II: Adjusted for age, gender, hypertension, diabetes mellitus, congestive heart failure, chronic pulmonary disease, alcohol consumption, cardiac arrhythmias, BUN, WBC, and the SIRS score
eGFR Estimated glomerular filtration rate, HR Hazard ratio, Ref Reference, CI Confidence interval, BUN Blood urea nitrogen, WBC White blood cell, SIRS score Systemic inflammatory response syndrome

ISSN: 1471-2253