Table 1 Baseline characteristics of participants by levels of estimated glomerular filtration rate (eGFR)
Characteristics | Â | Levels of eGFR (ml/min/1.73 m2) | ||||
|---|---|---|---|---|---|---|
Overall |  < 30 | 30–60 | 60–90 |  ≥ 90 | P-value | |
N = 493 | N = 118 | N = 111 | N = 106 | N = 158 |  | |
Demographics | ||||||
 Age | 60.15 (17.49) | 67.80 ± 18.31 | 68.10 ± 13.58 | 62.06 ± 15.71 | 47.58 ± 12.85 |  < 0.001 |
 Sex |  |  |  |  |  | 0.112 |
  Female | 231 (46.86%) | 64 (54.24%) | 45 (40.54%) | 54 (50.94%) | 68 (43.04%) |  |
  Male | 262 (53.14%) | 54 (45.76%) | 66 (59.46%) | 52 (49.06%) | 90 (56.96%) |  |
Clinical features, N (%) | ||||||
 Congestive heart failure |  |  |  |  |  < 0.001 | |
  No | 391 (79.31%) | 86 (72.88%) | 79 (71.17%) | 85 (80.19%) | 141 (89.24%) |  |
  Yes | 102 (20.69%) | 32 (27.12%) | 32 (28.83%) | 21 (19.81%) | 17 (10.76%) |  |
 Cardiac arrhythmias |  |  |  |  |  < 0.001 | |
  No | 342 (69.37%) | 72 (61.02%) | 69 (62.16%) | 70 (66.04%) | 131 (82.91%) |  |
  Yes | 151 (30.63%) | 46 (38.98%) | 42 (37.84%) | 36 (33.96%) | 27 (17.09%) |  |
 Hypertension |  |  |  |  |  |  < 0.001 |
  No | 218 (44.22%) | 37 (31.36%) | 45 (40.54%) | 44 (41.51%) | 92 (58.23%) |  |
  Yes | 275 (55.78%) | 81 (68.64%) | 66 (59.46%) | 62 (58.49%) | 66 (41.77%) |  |
 Chronic pulmonary disease |  |  |  |  | 0.26 | |
  No | 420 (85.19%) | 102 (86.44%) | 88 (79.28%) | 92 (86.79%) | 138 (87.34%) |  |
  Yes | 73 (14.81%) | 16 (13.56%) | 23 (20.72%) | 14 (13.21%) | 20 (12.66%) |  |
 Diabetes |  |  |  |  |  | 0.051 |
  No | 352 (71.40%) | 76 (64.41%) | 78 (70.27%) | 73 (68.87%) | 125 (79.11%) |  |
  Yes | 141 (28.60%) | 42 (35.59%) | 33 (29.73%) | 33 (31.13%) | 33 (20.89%) |  |
 Alcohol consumption |  |  |  |  | 0.739 | |
  No | 361 (73.23%) | 90 (76.27%) | 83 (74.77%) | 75 (70.75%) | 113 (71.52%) |  |
  Yes | 132 (26.77%) | 28 (23.73%) | 28 (25.23%) | 31 (29.25%) | 45 (28.48%) |  |
Blood biochemistry, mean (SD) | ||||||
 eGFR ml/min/1.73 m2 | 65.93 (38.56) | 16.07 ± 7.17 | 46.48 ± 8.64 | 73.97 ± 9.50 | 111.44 ± 15.68 |  < 0.001 |
 Creatinine, mg/dl | 1.10 (0.20–16.20) | 3.42 ± 2.12 | 1.45 ± 0.33 | 0.98 ± 0.20 | 0.68 ± 0.17 |  < 0.001 |
 BUN, mmol /L | 28.37 (22.21) | 53.19 ± 27.56 | 31.54 ± 14.12 | 20.19 ± 8.25 | 13.09 ± 6.66 |  < 0.001 |
 WBC, 10^9/L | 15.67 (7.72) | 15.83 ± 8.14 | 16.58 ± 8.45 | 16.04 ± 7.05 | 14.66 ± 7.24 | 0.211 |
 SOFA score, mean (SD) | 4.83 (3.56) | 7.86 ± 3.99 | 4.92 ± 2.78 | 4.00 ± 2.81 | 3.05 ± 2.59 |  < 0.001 |
 SIRS score, mean (SD) | 3.09 (0.86) | 3.04 (0.97) | 3.10 (0.86) | 3.16 (0.81) | 3.08 (0.82) | 0.783 |
 RRT, N (%) |  |  |  |  |  |  < 0.001 |
  No | 474 (96.15%) | 103 (87.29%) | 110 (99.10%) | 103 (97.17%) | 158 (100.00%) |  |
  Yes | 19 (3.85%) | 15 (12.71%) | 1 (0.90%) | 3 (2.83%) | 0 (0.00%) |  |
 ICU 28-day mortality, N (%) |  |  |  |  |  < 0.001 | |
  No | 434 (88.03%) | 87 (73.73%) | 98 (88.29%) | 98 (92.45%) | 151 (95.57%) |  |
  Yes | 59 (11.97%) | 31 (26.27%) | 13 (11.71%) | 8 (7.55%) | 7 (4.43%) |  |
 In-hospital mortality, N (%) |  |  |  |  |  < 0.001 | |
  No | 428 (86.82%) | 83 (70.34%) | 98 (88.29%) | 97 (91.51%) | 150 (94.94%) |  |
  Yes | 65 (13.18%) | 35 (29.66%) | 13 (11.71%) | 9 (8.49%) | 8 (5.06%) |  |
 In-ICU mortality, N (%) |  |  |  |  |  < 0.001 | |
  No | 445 (90.26%) | 90 (76.27%) | 103 (92.79%) | 100 (94.34%) | 152 (96.20%) |  |
  Yes | 48 (9.74%) | 28 (23.73%) | 8 (7.21%) | 6 (5.66%) | 6 (3.80%) |  |