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Table 2 Univariate and multivariate analysis of prognostic variables

From: Red blood cell distribution width/platelet ratio on admission as a predictor for in-hospital mortality in patients with acute myocardial infarction: a retrospective analysis from MIMIC-IV Database

Prognostic variables

Univariate analysis

Multivariate analysis

HR (95%CIs)

P-value

HR (95%CIs)

P-value

Demographics

    

Gender (men)

0.621 (0.401–0.959)

0.032

0.638 (0.368–1.106)

0.109

Age

1.031 (1.011–1.051)

0.002

1.031 (1.005–1.507)

0.019

Ethnicity (white)

0.455 (0.295-0.700)

< 0.001

0.403 (0.230–0.705)

0.001

Concomitant disease (n, %)

    

Hypertension

0.796 (0.492–1.288)

0.353

  

Diabetes mellitus

0.937 (0.605–1.452)

0.772

  

Cardiac arrhythmia

1.136 (0.726–1.778)

0.578

  

Heart failure

1.047 (0.680–1.612)

0.834

  

Pulmonary hypertension

0.582 (0.184–1.844)

0.358

  

Chronic pulmonary disease

1.492 (0.791–2.814)

0.216

  

Peripheral vascular disease

1.312 (0.677–2.541)

0.421

  

Cerebrovascular disease

0.601 (0.148–2.442)

0.476

  

Renal disease

1.440 (0.664–3.123)

0.356

  

Severe liver disease

1.413 (0.197–10.155)

0.731

  

Laboratory metrics

    

BUN (mg/dL)

1.018 (1.011–1.025)

< 0.001

1.001 (0.987–1.015)

0.884

Creatinine (mg/dL)

1.158 (1.071–1.251)

< 0.001

1.141 (0.972–1.340)

0.107

Troponin T (ng/mL)

1.079 (1.033–1.126)

0.001

1.026 (0.961–1.095)

0.449

CKMB (ng/mL)

1.004 (1.002–1.006)

< 0.001

1.003 (1.000-1.006)

0.04

Glucose (mg/dL)

1.005 (1.003–1.006)

< 0.001

1.004 (1.002–1.006)

< 0.001

Sodium (mEq/L)

0.934 (0.894–0.976)

0.002

0.947 (0.893–1.005)

0.075

Potassium (mEq/L)

1.311 (0.970–1.722)

0.078

  

RPR (cutoff 0.11)

2.750 (1.766–4.276)

< 0.001

2.677 (1.159–6.188)

0.021

Lymphocyte (K/ L)

0.944 (0.914–0.974)

< 0.001

0.979 (0.949–1.009)

0.169

Platelet (K/ L)

0.997 (0.995-1.000)

0.028

1.001 (0.998–1.005)

0.499

RBC (m/uL)

0.802 (0.602–1.068)

0.131

  

RDW (%)

1.181 (1.084–1.287)

< 0.001

0.999 (0.864–1.156)

0.993

Hemoglobin (g/dL)

1.025 (0.922–1.141)

0.645

  

MCH (pg)

1.026 (0.934–1.128)

0.589

  

MCHC (%)

0.825 (0.718–0.948)

0.007

0.989 (0.811–1.207)

0.915

MCV (fL)

1.047 (1.012–1.085)

0.009

1.037 (0.993–1.084)

0.102

Treatments

    

PCI

0.797 (0.421–1.508)

0.485

  

CABG

0.036 (0.005–0.256)

0.001

0.084 (0.011–0.623)

0.015

  1. Abbreviation: CK-MB = creatine kinase-MB; BUN = blood urea nitrogen; RPR = red blood cell distribution width/platelet ratio; RBC = red blood cell; RDW = red blood cell distribution width; MCH = mean corpuscular hemoglobin; MCHC = mean corpuscular hemoglobin concentration; MCV = mean corpuscular volume; PCI = percutaneous coronary intervention; CABG = coronary artery bypass grafting