Table 2 Primary and secondary outcomes

Number of hypotensive pts

7/17

13/17

Χ² = 4.37, P = 0.04²

Hypotensive events per patient

0.0 0.0 1.3

0.7 2.0 3.3

F = 6.94, P = 0.01³

Duration of hypotension (min)

0.0 0.0 2.2

0.7 3.7 7.8

F = 7.61, P = 0.01³

MAP during event (mmHg)

60.6 62 63.3

60 61.2 62.2

F = 0.02, P = 0.90³

AUT (mmHg x minutes)

0.6 2.0 15.2

3.6 16.7 43.3

F = 4.41, P = 0.04³

TWA of AUT (mmHg)

0 0.01 0.08

0.02 0.08 0.22

F = 4.33, P = 0.04³

Patients with MAP < 50 mmHg

0/17

2/17

Χ² = 2.13, P = 0.15²

Crystalloids (ml/kg/h)

9.5 11.8 14.5

11.1 13.6 16.2

F = 0.89, P = 0.35³

Colloids (ml/kg/h)

0.0 0.0 1.5

0.0 0.0 2.3

F = 0.14, P = 0.72³

RBC (ml/kg/h)

0.0 0.0 0.2

0.0 0.0 0.0

F = 2.47, P = 0.13³

Norepinephrine (µg/kg/min)

.01 .01 .02

.00 .01 .03

F = 0.09, P = 0.76³

Urine output (ml/kg/h)

2.3 2.7 3.6

2.6 3.4 5.1

F = 1.26, P = 0.27³

Lactate (mmol/L)

0.7 0.9 1.2

0.7 1.1 1.3

F = 0.68, P = 0.42³

BE (mmol/L)

-2.8 -1.0 0.8

-3.8 -1.7 -0.8

F = 1.61, P = 0.21³

pH

7.3 7.3 7.4

7.3 7.3 7.4

F = 1.01, P = 0.32³

ScVO₂ (%)

74.0 81.2 84.1

71.0 74.8 81.7

F = 1.22, P = 0.28³

Arterio-venous CO₂ gap (kPa)

0.7 0.9 1.1

0.5 0.9 1.2

F = 0.14, P = 0.71³

Mechanical ventilation (h)

0.0 0.0 2.2

0.0 0.0 0.0

F = 1.51, P = 0.23³

ICU stay (h)

19.0 21.5 28.7

19.7 22.0 22.0

F = 0.09, P = 0.77³

Hospital stay (d)

7.0 9.0 12.3

7.0 7.0 9.3

F = 2.23, P = 0.15³

Myocardial infarction (Y/N)

0/17

0/17

N/A

Cerebrovascular infarction (Y/N)

0/17

0/17

N/A

Acute kidney injury (Y/N)

0/17

1/16

Χ² = 1.03, P = 0.31²

Alive/dead at discharge

16/1

17/0

Χ² = 1.03, P = 0.31²

Alive/dead at day 28

16/1

17/0

Χ² = 1.03, P = 0.31²