Fig. 8From: Remote ischemic preconditioning and clinical outcomes after pediatric cardiac surgery: a systematic review and meta-analysisTrial sequential analysis plot of postoperative ICU length of stay (overall cohort). Trial sequential analysis of 11 RCTs that compared RIPreC versus control on postoperative ICU length of stay. The cumulative z curve crossed the conventional boundary but not the trial sequential monitoring boundary for benefit, indicating the current evidence is inconclusive. A required information size of 3,674 patients was calculated using α = 0.05 (two sided), β = 0.20 (power 80%) and the mean difference generated in the conventional meta-analysisBack to article page