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Table 1 Comparisons of baseline characteristics between the original cohort and matched cohort

From: Association between different MAP levels and 30-day mortality in sepsis patients: a propensity-score-matched, retrospective cohort study

Characteristic

Original cohort

   

Matched cohort

  
 

MAP

(60–65 mmHg)

MAP

(> 65 mmHg)

SMD

 

MAP

(60–65 mmHg)

MAP

(> 65 mmHg)

SMD

 

(n = 1305)

(n = 12,726)

  

(n = 1301)

(n = 1301)

 

female,n (%)

692 (53)

5805 (45.6)

0.149

 

689 (53)

716 (55)

0.042

Age (years)

72.1 ± 14.8

66.5 ± 16.4

0.359

 

72.0 ± 14.8

71.4 ± 14.0

0.047

Service unit, n (%)

  

0.257

   

0.031

MICU

782 (59.9)

6235 (49)

  

779 (59.9)

762 (58.6)

 

SICU/TSICU

225 (17.2)

3426 (26.9)

  

225 (17.3)

239 (18.4)

 

CCU/CSRU

298 (22.8)

3065 (24.1)

  

297 (22.8)

300 (23.1)

 

Weight (kg)

78.1 ± 23.9

81.1 ± 25.3

0.123

 

78.1 ± 23.9

77.5 ± 22.5

0.025

Vital signs

       

Heart rate (bpm)

85.8 ± 16.5

88.6 ± 16.4

0.176

 

85.7 ± 16.5

86.0 ± 16.5

0.013

Respiratory ate (bpm)

20.2 ± 4.5

19.8 ± 4.4

0.094

 

20.2 ± 4.5

20.5 ± 4.6

0.05

Temperature (℃)

36.8 ± 0.7

36.9 ± 0.7

0.168

 

36.8 ± 0.7

36.8 ± 0.7

0.018

SpO2 (%)

96.6 ± 3.8

97.0 ± 2.6

0.138

 

96.6 ± 3.8

96.5 ± 3.8

0.027

Severity of illness

       

Sofa

5.0 (4.0, 8.0)

5.0 (3.0, 7.0)

0.262

 

5.0 (4.0, 8.0)

5.0 (4.0, 8.0)

0.018

SapsII

45.6 ± 14.4

40.1 ± 13.9

0.384

 

45.5 ± 14.2

45.3 ± 15.4

0.013

Oasis

35.5 ± 8.7

34.5 ± 8.7

0.12

 

35.5 ± 8.7

35.4 ± 9.4

0.007

Comorbidities, n (%)

       

CHF

379 (29)

2934 (23.1)

0.137

 

377 (29)

379 (29.1)

0.003

Cardiac arrhythmias

388 (29.7)

3062 (24.1)

0.128

 

387 (29.7)

375 (28.8)

0.02

Hypertension

234 (17.9)

1761 (13.8)

0.112

 

233 (17.9)

232 (17.8)

0.002

Stroke

38 (2.9)

493 (3.9)

0.053

 

38 (2.9)

47 (3.6)

0.039

COPD

289 (22.1)

2725 (21.4)

0.018

 

287 (22.1)

276 (21.2)

0.021

Diabetes mellitus

403 (30.9)

3574 (28.1)

0.061

 

403 (31)

410 (31.5)

0.012

Renal failure

303 (23.2)

2125 (16.7)

0.164

 

302 (23.2)

305 (23.4)

0.005

Liver disease

138 (10.6)

1016 (8)

0.089

 

137 (10.5)

120 (9.2)

0.044

Malignancy

185 (14.2)

1316 (10.3)

0.117

 

181 (13.9)

158 (12.1)

0.053

Coagulopathy

305 (23.4)

2182 (17.1)

0.155

 

304 (23.4)

305 (23.4)

0.002

ELS, n (%)

       

RRT use (hours)

465 (35.6)

6556 (51.5)

0.325

 

465 (35.7)

448 (34.4)

0.027

MV use (hours)

90 (6.9)

606 (4.8)

0.091

 

90 (6.9)

86 (6.6)

0.012

Vasopressor use (hours)

247 (18.9)

2121 (16.7)

0.059

 

246 (18.9)

235 (18.1)

0.022

Laboratory tests

       

WBC (109/L)

13.2 (9.1, 18.7)

13.1 (9.3, 18.2)

0.029

 

13.2 (9.1, 18.7)

12.9 (9.1, 18.3)

0.004

Hemoglobin(g/dL)

9.4 ± 1.8

9.9 ± 2.1

0.283

 

9.4 ± 1.8

9.4 ± 2.0

0.008

Platelet (109/L)

183.0 (112.0, 261.0)

184.0 (121.0, 259.0)

0.022

 

183.0 (112.0, 261.0)

180.0 (118.0, 258.0)

0.001

Hematocrit (%)

28.1 ± 5.4

29.4 ± 6.1

0.227

 

28.1 ± 5.4

28.1 ± 5.9

0.001

INR

1.5 (1.2, 2.0)

1.3 (1.2, 1.7)

0.151

 

1.5 (1.2, 2.0)

1.4 (1.2, 1.9)

0.009

PT (seconds)

15.8 (13.9, 19.6)

14.8 (13.4, 17.4)

0.198

 

15.8 (13.9, 19.6)

15.3 (13.7, 19.3)

0.008

APTT (seconds)

36.5 (29.6, 52.0)

33.3 (27.9, 45.3)

0.14

 

36.5 (29.6, 52.0)

35.7 (28.8, 52.5)

0.003

Bun (mg/dL)

34.0 (21.0, 54.0)

25.0 (16.0, 41.0)

0.333

 

34.0 (21.0, 54.0)

33.0 (20.0, 53.0)

0.039

Creatinine (mg/dL)

1.5 (1.0, 2.5)

1.2 (0.8, 1.9)

0.209

 

1.5 (1.0, 2.5)

1.5 (1.0, 2.6)

0.004

Potassium (mmol/L)

3.8 (3.4, 4.3)

3.7 (3.4, 4.1)

0.192

 

3.8 (3.4, 4.3)

3.8 (3.4, 4.2)

0.016

Sodium (mmol/L)

135.5 ± 6.3

136.4 ± 5.6

0.159

 

135.5 ± 6.3

135.5 ± 7.2

0.001

Bicarbonate (mmol/L)

20.9 ± 5.5

21.9 ± 5.3

0.192

 

20.9 ± 5.5

20.8 ± 5.5

0.012

pH

7.4 ± 0.1

7.4 ± 0.1

0.102

 

7.4 ± 0.1

7.4 ± 0.1

0.012

PO2 (mmHg)

102.0 (70.0, 176.0)

116.0 (77.0, 209.0)

0.158

 

103.0 (70.0, 176.0)

99.0 (70.0, 163.0)

0.039

PCO2 (mmHg)

41.2 ± 12.0

41.9 ± 12.2

0.059

 

41.2 ± 12.0

40.7 ± 11.9

0.043

Lac (mmol/L)

2.2 (1.5, 3.5)

2.2 (1.4, 3.5)

0.056

 

2.2 (1.5, 3.5)

2.2 (1.4, 3.7)

0.028

Anion gap (mmol/L)

16.0 (14.0, 20.0)

16.0 (13.0, 19.0)

0.131

 

16.0 (14.0, 20.0)

16.0 (14.0, 20.0)

0.026

  1. MAP mean arterial pressure, MICU medical intensive care, SICU surgical intensive care unit, TSICU trauma surgical intensive care unit, CCU coronary care unit, CSRU cardiac surgery unit, SOFA Sequential Organ Failure Assessment, SAPS II Simplified Acute Physiology Score II, Oasis Oxford Acute Severity of Illness Score, ELS extracorporeal life support MV mechanical ventilation, RRT renal replacement therapy, CHF congestive heart failure, COPD chronic obstructive pulmonary disease, WBC white blood cell, INR international normalized ratio, PT prothrombin time, APTT activated partial thromboplastin time, BUN blood urea nitrogen, PO2 partial pressure of oxygen, PCO2 partial pressure of carbon dioxide, Lac lactic acid;
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BMC Anesthesiology

ISSN: 1471-2253

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