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Table 5 Multivariate logistic regression analysis of intraoperative serum high mobility group box 1 levels in the presence of pediatric acute respiratory distress syndrome

From: Association between serum HMGB1 elevation and early pediatric acute respiratory distress syndrome: a retrospective study of pediatric living donor liver transplant recipients with biliary atresia in China

Logistic regression model

PARDS

  

Non-adjusted

Adjust I

Adjust II

OR (95%CI), P

OR (95%CI), P

OR (95%CI), P

HMGB1(pg/ml)

1.41 (1.24, 1.61), < 0.0001

1.40 (1.23, 1.60), < 0.0001

1.28(1.10,1.49), 0.0017

HMGB1(pg/ml)(tertile)

   

 1st tertile(4.3–8.1 pg/mL)

1.0

1.0

1.0

 2nd tertile(8.2-10.6 pg/mL)

5.82 (1.86, 18.27), 0.0025

5.66 (1.79, 17.83), 0.0031

5.25(1.63,16.86), 0.0054

 3rd tertile(10.6–18.8 pg/mL)

14.33 (4.71, 43.56), < 0.0001

13.54 (4.42, 41.46), < 0.0001

7.75(2.35,25.57), 0.0008

  1. Adjust I model adjusted for age (month) and weight (kg); adjust II model adjusted for age (month), weight (kg), graft cold ischemia time (min), intraoperative blood loss volume (mL), pretransplant albumin (g/L), and pretransplant total bilirubin (µmol/L)
  2. Abbreviations: PARDS, pediatric acute respiratory distress syndrome; HMGB1, high mobility group box 1; OR, odds ratio; CI, confidence interval
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BMC Anesthesiology

ISSN: 1471-2253

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