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Table 2 Comparison of mechanical ventilation, vital signs and laboratory parameters between patients with successful and failed weaning

From: NT-proBNP change is useful for predicting weaning failure from invasive mechanical ventilation among postsurgical patients: a retrospective, observational cohort study

Variable

weaning success(n = 278)

weaning failure(n = 45)

P

RSBI(breaths/min/L)

36.17(31.05–42.23)

43.01(34.89–53.81)

0.001

Vte(ml)

470(425.75–488.5)

436(380.5–475.0)

0.033

RR(breaths/min)

18(16–22)

22(15.5–24.5)

0.067

MV(L/min)

7.99(6/687-8.363)

8.28(6.420–9.22)

0.256

 h((beats/min)

86.76 ± 15.41

89.76 ± 12.86

0.217

SBP(mmHg)

135.10 ± 19.95

131.04 ± 18.69

0.203

SPO2

99(97–100)

98(97–100)

0.179

PH

7.44(7.404–7.470)

7.44(7.42–7.477)

0.500

PaCO2(mmHg)

36.7(32.9–41)

36(31.75–40.85)

0.432

PaO2(mmHg)

108(86–138)

100(80.6-115.5)

0.044

PaO2/FIO2

312(246.31-397.23)

276.67(231-354.76)

0.071

HB(g/L)

101(88.75-120.25)

95(84.5-108.5)

0.018

ALB(g/L)

29.54 ± 4.56

26.84 ± 4.51

0.000

Creatinine(mmol/L)

67.6(51.15–91.9)

83.8(54.55-115.75)

0.045

β2 microglobulin(mmol/L)

2.97(2.32–3.95)

3.47(2.73–6.19)

0.007

NTproBNP1(pg/ml)

651(281.65-1315.25)

1221.5(404.5-3072.5)

0.005

NTproBNP2(pg/ml)

781.5(359.13-1504.75)

1946(842.35-4334.35)

0.000

ΔNT-proBNP%

11.9(2.425–60.74)

32.2(22.286–60.74)

0.000

Long diameter of left atrium(mm)

50(46–55)

49(45–54)

0.413

Transverse diameter of left atrium(mm)

35(32–38)

35(31.5–38)

0.567

Long diameter of right atrium(mm)

46(42–49)

46(42.5–50)

0.716

Transverse diameter of right atrium(mm)

32(29–35)

32(28–36)

0.867

Transverse diameter of right ventricle(mm)

30(28–32)

30(27.5–33)

0.658

Diameter of main pulmonary artery(mm)

24(22–25)

23(22–25)

0.756

LVDS(mm)

29(27–31)

31(30–32)

0.008

LVDD(mm)

47(44–49)

47(45–49)

0.270

LVEF(%)

67(63–71)

65(62.5–68)

0.007

Fluid balance during 24 h before SBT(ml)

403(-99.38-894)

642(18.5-1285.5)

0.091

  1. Note: Continuous variables were presented as median (25th-75th percentile) or (mean ± standard deviation, SD). Categorical variables were presented as numbers
  2. (n) and percentages (%). Difference of gender, medical history, and surgery sites between the groups were compared by Chi square (χ2) test. Difference of HR, SBP and ALB were compared by Student’s t test. Difference of other variables were compared by Mann-Whitney U-test
  3. Abbreviation: RSBI,rapid shallow breathing index; MV, minute volume; Vte, expired tidal volume; NT-proBNP, N-terminal prohormone B-type natriuretic peptide; HR, heart rate; RR, respiratory rate; SBP, systolic blood pressure; Hb, hemoglobin; ALB, albumin; LVDS, left ventricular end systolic diameter; LVDD, left ventricular end diastolic diameter; LVEF%, left ventricular ejection fraction;SBT, spontaneous breathing trial