NT-proBNP change is useful for predicting weaning failure from invasive mechanical ventilation among postsurgical patients: a retrospective, observational cohort study

Table 1 Baseline characteristics

Variable	Weaning success(n = 278)	Weaning failure(n = 45)	P
Age(years)	71.46 ± 12.72	73.98 ± 12.71	0.218
Gender
Male, n(%)	148(52.3)	24(53.3)	0.99
Female, n(%)	130(46.8)	21(46.7)
BMI(kg/m²)	24.88(22.22–27.68)	25.06(22.05–27.58)	0.701
APACHE II score at ICU admission	16(10.75-22)	21(12–23)	0.043
Medical history, n (%)
Chronic respiratory disorders	47(16.9)	3(6.7)	0.078
Coronary heart disease	66(23.7)	7(15.6)	0.223
Cerebral vascular disease	51(18.3)	5(11.1)	0.234
Tumor	84(30.2)	15(33.3)	0.728
Arrhythmia	18(6.5)	4(8.9)	0.526
Diabetes mellitus	92(33.1)	15(33.3)	0.975
Hypertension	162(58.3)	23(51.1)	0.368
Surgery sites, n (%)
Intra-abdominal	185(66.5)	27(60.0)	0.391
Orthopedic	37(13.3)	7(15.6)	0.684
Urological	22(7.9)	4(8.9)	1.000
Thoracic	22(7.9)	3(6.7)	1.000
Neurologic	9(3.2)	4(8.9)	0.167
others	3(1.1)	0(0)	1.000
IMV duration before SBT (days)	1(1–2)	2(2–3)	0.002
LOS in ICU(days)	3(2-5.25)	6(4–13)	0.000
LOS in hospital(days)	23(16–31)	25(17-34.5)	0.237

Note: Continuous variables were presented as median (25th-75th percentile) or (mean ± standard deviation, SD). Categorical variables were presented as numbers
(n) and percentages (%). Difference of gender, medical history, and surgery sites between the groups were compared by Chi square (χ2) test. Difference of age was compared by Student’s t test. Difference of BMI, APACHE II score, IMV duration before SBT, LOS in ICU and LOS in hospital were compared by Mann-Whitney U-test
Abbreviation: BMI, body mass index; IMV, invasive mechanical ventilation; APACHE II, acute physiology and chronic health evaluation II; LOS, length of stay; ICU, intensive care unit; SBT, spontaneous breathing trial

ISSN: 1471-2253