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Fig. 8 | BMC Anesthesiology

Fig. 8

From: Dexmedetomidine attenuates postoperative spatial memory impairment after surgery by reducing cytochrome C

Fig. 8

Immunofluorescence staining of hippocampus. (A) Representative microphotographs of Cytochrome c protein in CA1and CA3 areas of hippocampal sections from the three experimental groups. Compared to the control group and the Dex group, a higher intensity of the Cytochrome c protein was found in the model group at 3 days, but not 7 days after surgery (at × 63 magnification). (B) Representative microphotographs of Cytochrome c oxidase protein in CA1and CA3 areas of hippocampal sections from the three experimental groups. Compared to the Control group and the Dex group, a lower intensity of the Cytochrome c protein oxidase was found in the model group at 3 days, but not 7 days after surgery (at × 63 magnification). (C) Cytochrome c protein expression in the CA1 hippocampus of rats. (D) Cytochrome c protein expression in the CA3 hippocampus of rats. (E) Cytochrome c oxidase expression protein in the CA1 hippocampus of rats (F) Cytochrome c oxidase protein expression in the CA3 hippocampus of rats N = 3 per group. Data were analyzed by one-way ANOVA with Tukey’s multiple comparisons test. Scale bar = 20 μm. * P < 0.05 Compared with Model

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