Skip to main content
Fig. 5 | BMC Anesthesiology

Fig. 5

From: Dexmedetomidine attenuates postoperative spatial memory impairment after surgery by reducing cytochrome C

Fig. 5

Dexmedetomidine administration prevented surgery-induced mitochondrial structure damage in the CA1 and CA3 areas of hippocampus at 3 days. The hippocampus was harvested after the Morris maze test for observation under microscope. Dexmedetomidine was effective in reducing mitochondrial damage (Fig. 5A). Figure 5B represents mitochondrial number and area in hippocampus of three groups. Significantly decreased number of mitochondria were found in the hippocampi of Model group. On the contrary, mitochondrial area is significantly increased in the hippocampal tissues from Model group. The objects indicated by red arrows are mitochondria (magnification: × 8,000, scale bar in each panel = 1 μm)

Back to article page

BMC Anesthesiology

ISSN: 1471-2253

Contact us