Fig. 1From: Dexmedetomidine attenuates postoperative spatial memory impairment after surgery by reducing cytochrome CExperimental design. Thirteen-to fourteen-month-old rats were randomly allocated to the Control group (n = 18), the Model group (n = 18), and the Dex group (n = 18). Dexmedetomidine was administered every two hours, for a total of four times after surgery. All rats were trained in the MWM spatial acquisition trial and the probe trial. Open field test and new object recognition tasks were performed on the second day after surgery, mice were sacrificed and brain tissues subsequently harvested at two different time points after surgeryBack to article page