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Table 1 Patient characteristics for before SIPTW adjustment and after SIPTW adjustment

From: Outcomes of intravenous and inhalation anesthesia on patients undergoing esophageal cancer surgery: a retrospective observational study

Variable

BEFORE SIPTW ADJUSTMENT

AFTER SIPTW ADJUSTMENT

Group

INHA (n=216)

TIVA (n=147)

P

SMD

INHA (n=215.8)

TIVA (n=147.8)

P

SMD

Age

59

57

0.210

0.114

59

58

0.821

0.006

(Median [IQR] year)

[53.00, 63.25]

[53.00, 62.00]

  

[53.00, 63.00]

[53.00, 63.00]

  

Adjuvant treatment (%)

0.292

0.124

  

0.897

0.015

 No

125 (57.9)

76 (51.7)

  

117.5 (54.4)

79.3 (53.7)

 Yes

91 (42.1)

71 (48.3)

  

98.4 (45.6)

68.5 (46.3)

ASA (%)

0.513

0.123

  

0.990

0.016

 I

38 (17.6)

21 (14.3)

  

35.3 (16.4)

23.3 (15.8)

 Ii

158 (73.1)

108 (73.5)

  

158.5 (73.4)

109.5 (74.1)

 Iii

20 ( 9.3)

18 (12.2)

  

22.0 (10.2)

15.0 (10.2)

 BMI

22.1

22.5

0.717

0.076

22.1

22.1

0.525

0.021

  (Median [IQR] kg/m2)

[20.10, 24.83]

[20.30, 24.20]

  

[20.20, 24.99]

[20.22, 24.10]

Blood transfusion (%)

0.310

0.145

  

0.774

0.039

 No

206 (95.4)

144 (98.0)

  

207.8 (96.3)

141.2 (95.5)

 Yes

10 ( 4.6)

3 ( 2.0)

  

8.0 ( 3.7)

6.6 ( 4.5)

Cardiovascular disease (%)

1.000

0.031

  

0.963

0.005

 No

209 (96.8)

143 (97.3)

  

209.3 (97.0)

143.5 (97.1)

 Yes

7 ( 3.2)

4 ( 2.7)

  

6.5 ( 3.0)

4.3 ( 2.9)

Cerebrovascular disease (%)

0.476

0.099

  

0.934

0.009

 No

205 (94.9)

136 (92.5)

  

203.3 (94.2)

138.9 (94.0)

 Yes

11 ( 5.1)

11 ( 7.5)

  

12.5 ( 5.8)

8.9 ( 6.0)

Drink (%)

0.401

0.103

  

0.880

0.018

 No

75 (34.7)

44 (29.9)

  

70.4 (32.6)

49.4 (33.4)

 Yes

141 (65.3)

103 (70.1)

  

145.5 (67.4)

98.4 (66.6)

Diabetes (%)

0.114

0.192

  

0.657

0.056

 No

212 (98.1)

139 (94.6)

  

205.7 (95.3)

142.5 (96.4)

 Yes

4 ( 1.9)

8 ( 5.4)

  

10.1 ( 4.7)

5.3 ( 3.6)

 Duration of anesthesia

6.1

6.3

0.189

0.178

6.23

6.2

0.886

0.002

  (Median [IQR] h)

[5.00, 7.00]

[5.20, 7.35]

  

[5.00, 7.00]

[5.00, 7.30]

Degree of differentiation (%)

0.777

0.044

  

0.884

0.017

 Poor

165 (76.4)

115 (78.2)

  

165.4 (76.6)

114.3 (77.3)

 Well

51 (23.6)

32 (21.8)

  

50.5 (23.4)

33.5 (22.7)

Hypertension (%)

0.182

0.157

  

0.974

0.004

 No

186 (86.1)

118 (80.3)

  

181.0 (83.9)

124.2 (84.0)

 Yes

30 (13.9)

29 (19.7)

  

34.8 (16.1)

23.7 (16.0)

N (%)

0.009

0.329

  

0.985

0.020

 N0

117 (54.2)

61 (41.5)

  

103.7 (48.0)

70.6 (47.8)

 N1

58 (26.9)

62 (42.2)

  

72.2 (33.4)

48.7 (32.9)

 N2

41 (19.0)

24 (16.3)

  

40.0 (18.5)

28.5 (19.3)

 Postoperative hospital stay

16

15

0.906

0.038

16

15

0.921

0.010

  (Median [IQR] d)

[14.00, 18.25]

[14.00, 18.50]

  

[14.00, 18.00]

[14.00, 18.38]

 Preoperative HB

146.5

145.1

0.909

0.035

146.64

145

0.761

0.023

  (Median [IQR] g/l)

[135.93, 154.00]

[137.00, 154.40]

  

[136.23, 154.21]

[136.44, 154.76]

Pathological classification (%)

0.590

0.100

  

0.636

0.051

 Adenocarcinoma

6 ( 2.8)

2 ( 1.4)

  

4.5 ( 2.1)

2.1 ( 1.4)

 Squamous cell carcinoma

210 (97.2)

145 (98.6)

  

211.3 (97.9)

145.7 (98.6)

Sex (%)

1.000

0.003

  

0.931

0.009

 Female

6 ( 2.8)

4 ( 2.7)

  

5.3 ( 2.4)

3.4 ( 2.3)

 Male

210 (97.2)

143 (97.3)

  

210.6 (97.6)

144.4 (97.7)

Smoke (%)

0.333

0.116

  

0.919

0.012

 No

84 (38.9)

49 (33.3)

  

78.0 (36.1)

52.6 (35.6)

 Yes

132 (61.1)

98 (66.7)

  

137.8 (63.9)

95.2 (64.4)

 The length of the operation

5.2

5.3

0.160

0.194

5.2

5.11

0.756

0.004

  (Median [IQR] h)

[4.07, 6.10]

[3.95, 6.40]

  

[4.10, 6.20]

[3.80, 6.17]

Surgical type (%)

0.835

0.095

  

0.988

0.039

 Lvor lewis

86 (39.8)

58 (39.5)

  

83.6 (38.7)

54.8 (37.1)

 Mckeown

55 (25.5)

37 (25.2)

  

54.7 (25.3)

38.4 (26.0)

 Sweet

74 (34.3)

50 (34.0)

  

76.3 (35.4)

53.5 (36.2)

 Thoracoabdominal incision

1 ( 0.5)

2 ( 1.4)

  

1.2 ( 0.6)

1.1 ( 0.7)

Tumor location (%)

0.739

0.083

  

0.956

0.035

 Lower esophagus

96 (44.4)

67 (45.6)

  

96.5 (44.7)

64.0 (43.3)

 Middle esophagus

105 (48.6)

67 (45.6)

  

100.7 (46.6)

69.9 (47.3)

 Upper esophagus

15 ( 6.9)

13 ( 8.8)

  

18.7 ( 8.6)

14.0 ( 9.4)

T (%)

0.884

0.086

  

0.986

0.040

 T1

51 (23.6)

32 (21.8)

  

48.6 (22.5)

34.6 (23.4)

 T2

40 (18.5)

32 (21.8)

  

44.1 (20.4)

31.7 (21.4)

 T3

121 (56.0)

80 (54.4)

  

119.5 (55.4)

79.4 (53.7)

 T4

4 ( 1.9)

3 ( 2.0)

  

3.6 ( 1.7)

2.1 ( 1.5)

TNM (%)

0.261

0.177

  

0.999

0.004

 I

46 (21.3)

23 (15.6)

  

39.9 (18.5)

27.5 (18.6)

 Ii

75 (34.7)

48 (32.7)

  

72.0 (33.4)

49.2 (33.3)

 Iii

95 (44.0)

76 (51.7)

  

104.0 (48.2)

71.1 (48.1)

 Total hospital stay

24

24

0.627

0.029

24

24

0.567

0.017

  (Median [IQR] d)

[21.00, 28.00]

[21.00, 28.50]

  

[21.00, 27.04]

[21.00, 29.00]

  1. Abbreviations: IQR Inter-quartile range, ASA American society of anesthesiologists, BMI Body mass index, INHA Inhalational anesthesia, TIVA Total intravenous anesthesia, SIPTW Stabilized inverse probability of treatment weighting, SMD Standardized mean difference