Non-thyroidal Illness Syndrome (NTIS) is no independent predictor for mortality in ICU patients

BMC Anesthesiology

Table 3 Hospital mortality NTIS Low fT3 and NTIS Low fT3 fT4

	NTIS Low fT3				NTIS Low fT3 fT4
parameters	regression coefficient	Odds Ratio	95% confidence levelfür Odds Ratio		regression coefficient	Odds Ratio	95% confidence levelfür Odds Ratio
			lower value	upper value			lower value	upper value
age	0.039	1.040	1.022	1.057	0.049	1.050	1.030	1.071
SAPS II	0.014	1.014	1.002	1.026	0.013	1.013	0.999	1.027
mech. ventilation	0.789	2.201	1.278	3,790	1.198	3.312	1.480	7.411
pneumonia	0.032	1.032	0.618	1.725	-0.360	0.698	0.370	1.316
ARDS	0.943	2.567	1.022	6.446	0.215	1.239	0.490	3.133
AKI	1.539	4.661	2.592	8,380	1.305	3.687	1.890	7.192
sepsis	0.718	2.051	1.122	3.749	1.178	3.247	1.599	6.592
liver failure	1.328	3.772	1.408	10.104	3.387	29.581	8.425	103.860
NTIS	0.080	1.084	0.728	1.614	0.115	1.122	0.670	1.878
constant	-5.587				-6.545

Multivariate logistic regression of risk factors for hospital mortality of patients with NTIS Low fT3; binary logistic regression including n = 381 patients with NTIS Low fT3 and n = 284 patients with NTIS Low fT3 fT4 after Propensity-Score adjustment (in terms of age, gender, height, body mass index and SAPS at admission ICU)
SAPS Simplified Acute Physiology Score, mech Mechanical, ARDS Acute Respiratory Distress Syndrome, AKI Acute kidney injury, ICD-10 International Classification of Diseases; Hosmer–Lemeshow-Test
p = 0.740; Nagelkerke`s R² 0.362/ 0.555; Modell Chi² 213.14/ 327.98; p < 0.001; sensitivity: 44.7% (85/190)/ 63.1% (113/179) correctly predicted deceased; specificity: 94.9% (543/572)/ 93.8% (365/389) correctly predicted survivors

ISSN: 1471-2253