Table 1 Univariate analysis and Baseline parameters of all three groups
From: Non-thyroidal Illness Syndrome (NTIS) is no independent predictor for mortality in ICU patients
|  | Non-NTIS-group(n=1125) | NTIS Low fT3-group(n=381) | NTIS Low fT3 fT4-group(n=284) | P Kruskal Wallis/ Chi² |
|---|---|---|---|---|
baseline parameters | ||||
age, years; MD (IQR) | 59 ( 44-72) | 68 (56-77)* | 61 (52-74)*§ | < 0,001 |
male; n (%) | 694 (62) | 217 (57) | 176 (62) | 0.235 |
height, cm; MD (IQR) | 172 (165-180) | 170 (165-178) | 174 (168-180)§ | 0.019 |
weight, kg; MD (IQR) | 75 (65-85) | 75 (65-85) | 75 (66-88) | 0.526 |
BMI, kg/m²; MD (IQR) | 25 (23-28) | 25,4 (23-28) | 25,2 (23-29) | 0.951 |
SAPS II at admission; MD (IQR) | 33 (22-48) | 41 (32-56)* | 44 (32-57)* | < 0,001 |
thyroid hormones | ||||
TSH, mU/l; MD (IQR) | 2,24 (0,54-4,87) | 0,49 (0,23-1,33) * | 0,63 (0,23-1,88) * | < 0,001 |
fT3, pmol/l; MD (IQR) | 3,86 (3,20-4,73) | 2,47 (2,12-2,80) * | 2,10 (1,62-2,54) *§ | < 0,001 |
fT4, pmol/l; MD (IQR) | 16,3 (13,9-19,1) | 15,7 (14,1-17,3) | 10,4 (9,0-11,7) *§ | < 0,001 |
diagnosis, procedures | ||||
sepsis; n (%) | 106 (9) | 62 (16) * | 99 (35) *§ | < 0,001 |
pneumonia; n (%) | 140 (12) | 76 (20) | 99 (35) *§ | < 0,001 |
ARDS; n (%) | 35 (3) | 21 (6) * | 37 (13) *§ | < 0,001 |
mech. ventilation; n (%) | 653 (58) | 281 (74) * | 252 (89) *§ | < 0,001 |
mech. ventilation, hrs; MD (IQR) | 38 (5-211) | 147 (18-368) * | 198 (58-485) *§ | < 0,001 |
AKI; n (%) | 99 (9) | 64 (17)* | 105 (37) *§ |  |
liver disease; n (%) | 237 (21) | 89 (23) | 93 (33) *§ | < 0,001 |
liver failure; n (%) | 41 (4) | 30 (8) * | 47 (17) *§ | < 0,001 |
intracranial hemorrhage/ lesion; n (%) | 360 (32) | 91 (24) * | 72 (25) | 0.003 |
diabetes mellitus; n (%) | 226 (20) | 111 (29)* | 72 (25) | 0.001 |
length of stay, mortality | ||||
ICU-LOS, d; MD (IQR) | 8 (3-18) | 15 (6-28) * | 23 (10-40) *§ | <0,001 |
hospital-LOS, d; MD (IQR) | 21 (11-36) | 28 (17-45) * | 32 (19-59) * | <0,001 |
ICU-mortality; n (%) | 155 (14) | 75 (20)* | 105 (37) *§ | <0,001 |
hospital-mortality; n (%) | 185 (16) | 105 (28)* | 116 (41) *§ | <0,001 |