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Table 1 Baseline patient characteristics

From: Low tidal volume ventilation for patients undergoing laparoscopic surgery: a secondary analysis of a randomised clinical trial

 

Overall

(n = 328)

Low Tidal Volume

(n = 158)

Conventional Tidal Volume

(n = 170)

p value

Age (years)

63 (55–71)

63 (56–71)

62 (55–71)

0.667

Male gender (no. [%])

198 (60.4)

99 (62.7)

99 (58.2)

0.431

Weight (kg)

81.0 (69.8–96.0)

81.0 (68.0–97.0)

80.5 (71.8–95.8)

0.959

BMI (kg/m2)a

28.1 (24.5–32.6)

28.1 (24.2–32.6)

28.1 (24.8–32.3)

0.739

ARISCAT score (no. / N [%])b

32.5 (25.5–41.0)

31.0 (26.0–41.0)

34.0 (23.0–41.0)

0.712

 Low risk

60 / 240 (25.0)

25 / 119 (21.0)

35 / 121 (28.9)

0.288

 Moderate risk

158 / 240 (65.8)

84 / 119 (70.6)

74 / 121 (61.2)

 High risk

22 / 240 (9.2)

10 / 119 (8.4)

12 / 121 (9.9)

ASA physical status (no. / N [%])c

   

0.563

 1: healthy

26 / 323 (8.0)

10 / 156 (6.4)

16 / 167 (9.6)

 

 2: mild systemic disease

142 / 323 (44.0)

66 / 156 (42.3)

76 / 167 (45.5)

 

 3: severe systemic disease

143 / 323 (44.3)

73 / 156 (46.8)

70 / 167 (41.9)

 

 4: constant threat to life

12 / 323 (3.7)

7 / 156 (4.5)

5 / 167 (3.0)

 

Baseline SpO2 (%)

97 (96–98)

97 (96–98)

97 (96–98)

0.619

Baseline HCO3 (mmol/L)

26 (24.5–28)

26 (24–28)

26 (25–28)

0.291

Baseline haemoglobin (g/dL)

139 (123–150)

141 (127–152)

138 (122–149)

0.083

Baseline creatinine (mg/dL)

0.88 (0.74 − 1.07)

0.89 (0.74 − 1.06)

0.87 (0.72–1.08)

0.615

Comorbidities (no. / N [%])

 Diabetes

63 / 328 (19.2)

28 / 158 (17.7)

35 / 170 (20.6)

0.575

 Hypertension

170 / 328 (51.8)

81 / 158 (51.3)

89 / 170 (52.4)

0.912

 Obesityd

123 / 320 (38.4)

55 / 153 (35.9)

68 / 167 (40.7)

0.421

 Coronary artery disease

54 / 328 (16.5)

24 / 158 (15.2)

30 / 170 (17.6)

0.556

 Chronic kidney disease

28 / 328 (8.5)

12 / 158 (7.6)

16 / 170 (9.4)

0.693

 Chronic liver disease

28 / 328 (8.5)

9 / 158 (5.7)

19 / 170 (11.2)

0.112

 Smoking

58 / 328 (17.7)

33 / 158 (20.9)

25 / 170 (14.7)

0.150

 Chronic obstructive pulmonary disease

39 / 328 (11.9)

20 / 158 (12.7)

19 / 170 (11.2)

0.734

 Asthma

28 / 328 (8.5)

10 / 158 (6.3)

18 / 170 (10.6)

0.235

 Obstructive sleep apnoea

38 / 328 (11.6)

16 / 158 (10.1)

22 / 170 (12.9)

0.491

 Recent respiratory infection

6 / 328 (1.8)

5 / 158 (3.2)

1 / 170 (0.6)

0.110

Emergency surgery (no. [%])

9 (2.7)

7 / 158 (4.4)

2 (1.2)

0.094

  1. Data are median (25th–75th quartile) or N (%)
  2. Abbreviations: BMI Body Mass Index, ARISCAT Assess Respiratory Risk in Surgical Patients in Catalonia, ASA American Society of Anesthesiologists, HCO3 bicarbonate, SpO2 pulse oximetry
  3. aCalculated as weight in kilograms divided by height in metres squared
  4. bScore range is from 0 to 123; higher scores indicate a higher risk of postoperative pulmonary complications. Patients with scores of 26 or greater are considered at intermediate risk; those with a score greater than 44 are considered at high risk
  5. cScores on the ASA (American Society of Anesthesiologists) physical status classification system ranges from 1 to 6, with higher scores indicating more severe condition
  6. dDefined as BMI > 30 kg/m2
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BMC Anesthesiology

ISSN: 1471-2253

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