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Table 1 General characteristics of included studies

From: Neutrophil to lymphocyte ratio and platelet to lymphocyte ratio as prognostic predictors for delirium in critically ill patients: a systematic review and meta-analysis

First author

Year

Design

Type of critical condition

Delirium group

Non-delirium group

NOS score

NLR Cut-off point

SEN

SP

Delirium Definition

N

NLR

PLR

N

NLR

PLR

Mean

SD

Mean

SD

Mean

SD

Mean

SD

Guliyev,E

2016

P

-

30

29.22

5.20

101.29

11.01

34

29.42

5.13

102.71

12.22

9

-

-

-

DSM-IV

Egberts,A

2017

R

-

13

9.10

5.61

-

-

73

5.18

3.05

-

-

8

-

-

-

DSM-IV & V

Theologou,S

2018

P

POD

20

4.60

4.80

-

-

159

3.10

3.00

-

-

8

-

-

-

RASS and CAM-ICU

Kotfis,K.1

2019

P

PSD

121

6.71

9.65

-

-

639

4.55

5.51

-

-

7

-

-

-

CAM-ICU & DSM-Va

Kotfis,K.2

2019

P

PSD

172

4.74

4.05

-

-

829

3.43

2.25

-

-

8

4.86

42%

74%

CAM-ICU & DSM-Va

Kotfis,K.3

2019

R

POD

129

2.56

1.45

109.87

46.38

839

2.47

1.30

120.36

52.98

7

-

-

-

CAM-ICU & DSM-Va

He,R

2020

P

POD

182

4.67

1.62

-

-

598

2.68

1.26

-

-

6

3.5

75%

74%

CAM & DSM-IV

Ida,M

2020

R

POD

61

3.11

3.30

138.50

70.70

772

3.04

2.50

175.40

120.00

8

-

-

-

Validated chart-based method

Jiang,X

2020

R

-

29

17.10

12.70

306.50

240.50

290

13.60

10.90

202.20

144.90

7

-

-

-

CAM-ICU

Kalyoncuoglu,M

2020

R

POD

17

5.20

5.49

-

-

61

2.87

1.36

-

-

7

-

-

-

RASS & CAM-ICU

Yenibertiz,D

2020

R

-

126

15.86

12.89

345.86

211.93

86

10.10

11.23

235.70

209.08

8

-

-

-

DSM-V

Dardes,D

2021

P

PCD

14

9.37

8.91

-

-

42

6.02

5.14

-

-

7

-

-

-

4AT & CAM-ICU

Garcia-Grimshaw,M

2021

R

PCD

166

13.50

7.97

-

-

851

9.24

7.03

-

-

9

2.5

70%

52%

CAM-ICU & CAM brief versionb

Guldolf,K

2021

R

PSD

201

3.96

2.76

-

-

313

2.66

1.78

-

-

8

-

-

-

DSM-V

Katipoglu,

2021

R

-

170

23.35

15.96

-

-

445

10.2

5.82

-

-

7

-

-

-

DSM

Kinoshita,H

2021

R

POD

20

4.16

1.94

-

-

77

1.94

0.77

-

-

8

-

-

-

ICDSC

Kotfis,K.4

2021

R

PCD

39

9.25

6.81

280.95

170.56

162

5.75

4.91

263.70

183.03

7

-

-

-

DSM V

Lechowicz,K

2021

R

POD

164

3.43

3.02

135.10

73.60

934

3.11

2.92

132.42

69.17

9

-

-

-

CAM-ICU & DSM-Va

Li,D

2021

R

-

393

15.23

12.46

-

-

864

17.45

12.98

-

-

8

-

-

-

CAM-ICU

Zhao, Y

2021

P

-

101

    

639

    

7

3.62

75%

63%

CAM

Oyama,T

2022

R

POD

20

3.34

1.42

171.66

62.23

90

2.23

1.31

161.33

61.02

8

2.45

85%

63%

ICDSC

Reznik,M.E

2021

R

PSD

157

9.00

10.40

-

-

127

6.40

5.50

-

-

7

-

-

-

DSM-V

Giorgi, D

2022

R

PCD

46

8.54

3.55

-

-

168

4.15

0.76

-

-

7

-

-

-

4AT& DSM

Li, J

2022

R

POD

48

5.62

3.89

-

-

48

3.98

1.98

-

-

7

-

-

-

DSM

  1. R Retrospective, P prospective, POD Post-operative delirium, PSD Post-stroke delirium, PCD Post-COVID delirium, N Number, SD standard deviation, NLR Neutrophil to lymphocyte ratio, PLR Platelet to lymphocyte ratio, NOS Newcastle–Ottawa scale, SEN Sensitivity, SP Specificity
  2. aCAM-ICU was used for screening, followed by DSM-V for confirmatory diagnosis
  3. bAll diagnoses confirmed by attending psychiatrist or neurologist
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BMC Anesthesiology

ISSN: 1471-2253

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