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Table 2 Clinical and hemodynamic outcomes

From: Evaluating an advanced double intravenous vasopressor automated system to treat hypotension during spinal anesthesia for cesarean delivery: a randomized controlled trial

Variable

ADIVA (n = 46)

DIVA (n = 48)

p-value

Incidence of hypotension a,b

36 (78.3)

40 (83.3)

0.677

Incidence of hypertension a,c

43 (93.5)

40 (83.3)

0.199

Incidence of bradycardia a,d

0 (0.0)

0 (0.0)

-

Minimum SBP (mmHg) a

69.8 ± 21.0

69.2 ± 17.0

0.881

Maximum SBP (mmHg) a

163.4 ± 46.7

154.4 ± 41.6

0.323

SBP readings within 80% to 120% of baseline a

93,432/125,966 (74.2)

109,458/128,991 (84.9)

< 0.001

SBP readings below 80% of baseline a

11,105/125,966 (8.8)

7460/128,991 (5.8)

< 0.001

Minimum heart rate (beats.min−1) a

51.2 ± 13.9

54.3 ± 14.8

0.300

Maximum heart rate (beats.min−1) a

115.9 ± 14.9

116.7 ± 17.4

0.812

Total phenylephrine dose (μg) a

100 (150) [0 to 400]

150 (250) [0 to 1150]

0.014

Total ephedrine dose (mg) a

0 (0) [0 to 16]

0 (0) [0 to 8]

0.504

Total intravenous fluid volume (ml) a

500 (300) [200 to 1000]

550 (100) [150 to 1500]

0.229

Incidence of nausea a

7 (15.2)

10 (20.8)

0.595

Incidence of vomiting a

6 (13.0)

8 (16.7)

0.774

Fetal weight (g)

3200 ± 340

3100 ± 360

0.679

Apgar score (1 min)

9 [8 to 9]

9 [8 to 9]

1.000

Apgar score (5 min)

9 [9 to 9]

9 [9 to 9]

Umbilical arterial pH

6.9 ± 1.5

5.8 ± 3.0

0.019

Umbilical venous pH

7.2 ± 1.1

7.2 ± 1.1

0.955

Umbilical arterial lactate

2.4 ± 0.9

2.1 ± 1.4

0.157

Umbilical venous lactate

1.7 ± 0.5

1.8 ± 0.5

0.441

  1. Values are expressed in mean ± standard deviation (SD) or median (interquartile range (IQR) [range]) or number (%)
  2. ADIVA Advanced double intravenous vasopressor automated, DIVA Double intravenous vasopressor automated, SBP Systolic blood pressure
  3. a During the period from spinal anesthesia to fetal delivery
  4. b Defined as any SBP reading below 80% of baseline
  5. c Defined as any SBP reading above 120% of baseline
  6. d Defined as any heart rate reading below 60 beats.min−1