Table 1 Summary of findings table
Author (Year) | Group 1 | Group 2 | Country | Age | ASA | LA1 | LA2 | GA protocol | PO analgesia protocol | Main Outcome | |
|---|---|---|---|---|---|---|---|---|---|---|---|
Zhang Y (2021) [19] | PIFB | PLACEBO | China | 20–70 | 3–4 | 0.4% ropivacaine 20 ml | Saline 20 mL | INDUCTION: MDZ 0.05—0.1 mg/kg. SUF 0.8—1 μg/kg.; ETM 0.3 mg/kg and ROC 0.6 mg/kg MAINTENANCE: SUF. PRP and ROC | PCA SUF and 20 mg parecoxib iv at 6 h intervals | Postoperative pain | |
Athar M (2021) [20] | ESPB | PLACEBO | India | 18–60 |  | 0.25% levobupivacaine 20 ml | Saline 20 mL | PREMEDICATION: diazepam 0.2 mg/kg INDUCTION: FNT 5 mcg/kg. ETM 0.3–0.6 mg/kg, ROC 0.6–1 mg/kg MAINTENANCE: SEVO 1–2%. FNT 5–10 mcg/kg/h |  | Fentanyl comsumption | |
Kumar AK (2021) [21] | PIFB | IV ANALGESIC | India | 18–80 |  | Ropivacaine 0.25% 10 ml | Saline 10 mL | INDUCTION: FNT. 2 mg/kg. THP 2–3 mg/kg. ROC 1 mg/kg. MAINTENANCE: isoflurane, FNT and ROC | Acetaminophen iv 1 g. and tramadol 50 mg every 6 h | Postoperative pain | |
Khera T (2021) [22] | PIFB | PLACEBO | USA |  > 18 |  | 0.25% bupivacaine 20 ml | Saline 20 mL |  |  | Morphine comsumption | |
Aydin ME (2020) [23] | TTMPB | PLACEBO | Turkey |  | 2–3 | 20 ml of 0.25% bupivacaine | Saline 20 mL | INDUCTION: MDZ 0.5 mg/kg; THP 5 mg/kg, ROC 0.6 mg/kg, REMI 0.5 mg/kg bolus MAINTENANCE: REMI 0.15—0.35 mg/kg/min | Tramadol 100 mg if VAS ≥ 4 | Fentanyl comsumption | |
Krishna SN (2019) [24] | ESPB | IV ANALGESIC | India | 20–70 |  | 3 mg/kg of 0.375% ropivacaine 20 to 25 ml | Not given | INDUCTION: FNT 1 mg/kg, MDZ 0.05 mg/kg, HP 3 -5 mg/kg, ROC 0.6 mg/kg MAINTENANCE: isoflurane and boluses of atracurium and FNT | Tramadol or FNT iv | Postoperative pain | |
Chen H (2021) [25] | PIFB | PLACEBO | China | 18–65 | 1–2 | Ropivacaine 0.5% 10 mL | Saline 10 mL | MAINTENANCE: SEVO and REMI. Cisatracurium | PCA-SUF 1.5—2.5 mcg/h and boluses of 1 mcg 10 min lockout interval (Max dose: 8 mcg/h) | Cumulative sufentanil consumption | |
Hamed. M. A. (2022) [26] | PIFB | PLACEBO | Egypt |  > 18 |  | Bupivacaine 0.25% 20 mL plus 5 mcg/mL epinephrine | Dry needle | INDUCTION: MDZ 2 mg, FNT 10 mcg/kg, PRP 2 mg/kg. atracurium 0.5 mg/kg MAINTENANCE: isoflurane 1%. atracurium 0.5 mg/kg | IV morphine 5–10 mg boluses (required) | Cumulative morphine consumption | |
Kaya C (2021) [27] | PIFB | TTMPB | Turkey | 18–80 | 2–3 | Bupivacaine 0.25% 20 mL plus 1:400,000 epinephrine | Bupivacaine 0.25% 20 mL plus 1:400,000 epinephrine | INDUCTION: MDZ 0.05–0.1 mg/kg, FNT 2–5 mcg/kg, pentothal 4–5 mg/kg. ROC 1 mg/kg MAINTENANCE: SEVO 1–2%. FNT 2–5 mcg/kg/h | Acetaminophen 1 g × 4. PCA: 20 mcg/kg morphine lockout time: 6–10 min, tramadol 100 mg (NRS > 3) | Morphine comsumption | |
Shokri H (2021) [28] | TTMPB | PLACEBO | Egypt | 55–74 | 2–3 | Bupivacaine 0.25% 15 mL | Saline 15 mL | PREMEDICATION: MDZ 1–3 mg INDUCTION: FNT 5–6 mcg/kg, PRP 2 mg/kg. ROC 0.6 mg/kg MAINTENANCE: isoflurane 1–2% | 4 × 1gr paracetamol. morphine 0.05 mg/kg (VAS > 4) | Morphine comsumption | |
Fujii S (2019) [29] | TTMPB | IV ANALGESIC | Canada | 18–90 |  | Ropivacaine 0.3(weighing < 75 kg) -0.5 (> 75 kg) % 20 mL | No block | INDUCTION: PRP 0.5–1 mg/kg, MDZ 0.05–1 mg/kg, FNT 2–5 mcg/kg, ROC 0.6–1 mg/kg MAINTENANCE: isoflurane 0.5–1% | Hidmorphone, Acetaminophen, NSAID | Recruitment rate. Adherence rate. Adverse events rate | |
Zhang (2021) [30] | TTMPB | IV ANALGESIC | China | 18–70 | 2–3 | Ropivacaine 0.4% 20 mL | Saline 20 mL | INDUCTION: MDZ 0.1 mg/kg, ETM 0.3 mg/kg, cisatracurium 0.15 mg/kg, SUF 0.6–1 mcg/kg MAINTENANCE: PRP and cisatracurium | Sufentanyl iv additional pain: 4 × 50 mg flurbiprofen | Perioperative sufentanil consumption | |
Kumar K (2018) [31] | IV ANALGESİC | PECS I | India | 25–65 |  | No block | Bupivacaine 0.25% + dexmetedomidine 25 mcg 30 mL and bupivacaine 0.25% 5 mL |  |  | Paracetamol 1 gr + tramadol 50 mg iv + fentanyl 1 mcg/kg (VAS > 4 rescue analgesia) and diclofenac 75 mg (VAS > 4 30 min after first rescue analgesia) | Postoperative pain |
Hamed (2022) [32] | TTMPB | PLACEBO | Egypt |  > 18 |  | 20 mL of 0.25% bupivacaine | 20 mL of 0.9% saline | PREMEDICATION: 10 mg morphine im INDUCTION: MDZ 2 mg, FNT (10 μg.kg − 1), PRP (3 mg.Kg − 1), and atracurium (0.5 mg.kg − 1) MAINTENANCE: Isoflurane 0.4%—1%, atracurium 0.5 mg/kg/h, PRP 50–100 μ/kg/min | IV FNT PCA with (10 μg/mL, bolus of 15 μg, lockout 10 min—MAX 90μ/hr). Acetaminophene 1 g every 8 h | Total fentanyl consumption | |
Guven (2022) [33] | ESPB | IV ANALGESIC | Turkey | 18–65 | 1–2 | 20 ml of 0.25% bupivacaine | No block | PREMEDICATION: MDZ 0.03 mg/kg INDUCTION: FNT 1 µg/kg, MDZ 0.15 mg/kg, PRP 1–2 mg/kg, ROC 1 mg/kg. MAINTENANCE: SEVO, ROC infusion (0.01 mg/kg/min) and FNT (2–3 µg/kg/h) | Acetaminophen 1 g, 100 mg IV tramadol, IV PCA with morphine (0.5 mg/ml concentration, 1 mg bolus dose, lockout 10 min) | Total morphine consumption | |