Determining the effective dose of esketamine for mitigating pain during propofol injection by Dixon’s up-and-down method: a double-blind, prospective clinical study of drug dose response

Table 2 Comparison of the experimental conditions of the two groups of patients

Group	Number of cases (n)	Esketamine (mg/kg)	Surgical duration (min)	Awakening time (min)	VRS score	VAS score	SAS score
Effective	14	0.16 ± 0.2	10 ± 1.1	8.7 ± 1.1	0 ± 0	1.1 ± 0.4	3.8 ± 0.4
Ineffective	11	0.14 ± 0.2^a	9.4 ± 1.2	8.4 ± 1.2	1.3 ± 0.5^a	1.4 ± 0.5	3.9 ± 0.3

Values are expressed as mean ± SD or number of patients. Compared with the effective group, ^a P < 0.05

ISSN: 1471-2253