Predictive parameters | All OSA (AHI ≥5) | Moderate-to-Severe OSA (AHI ≥15) | Severe OSA (AHI ≥30) |
---|---|---|---|
(4 studies, n = 1160) | (8 studies, n = 2812) | (5 studies, n = 2447) | |
Prevalence (%) | 65 (62 to 68) | 38 (36 to 40) | 17 (16 to 19) |
Sensitivity (%) | 85 (82 to 88) | 88 (85 to 89) | 90 (87 to 93) |
Specificity (%) | 47 (42 to 52) | 29 (27 to 32) | 27 (25 to 29) |
Positive predictive value (%) | 74.9 (71.8 to 77.7) | 42.9 (40.8 to 45.0) | 20.3 (18.5 to 22.2) |
Negative predictive value (%) | 62.7 (56.9 to 68.1) | 79.6 (76.2 to 82.6) | 93.2 (90.9 to 95.1) |
Diagnostic odds ratio | 4.63 (2.76 to 7.75) | 3.36 (2.67 to 4.21) | 4.17 (2.74 to 6.35) |
AUC | 0.8437 SE = 0.0531 | 0.6729 SE = 0.0351 | 0.6302 SE = 0.0488 |
Likelihood ratio (+) | 1.56 (1.21 to 2.01) | 1.24 (1.16 to 1.32) | 1.27 (1.20 to 1.34) |
Likelihood ratio (−) | 0.37 (0.30 to 0.46) | 0.40 (0.31 to 0.52) | 0.27 (0.14 to 0.52) |
Post-test probability (%; positive test) | 74.5% | 42.9% | 20.6% |
Post-test probability (%; negative test) | 40.9% | 19.5% | 5.2% |