Predictors of hypotension during anesthesia induction in patients with hypertension on medication: a retrospective observational study

Table 4 Explanatory variables and variable categories significantly associated with hypotension during anesthesia induction in patients with hypertension

Explanatory variables	aOR (95% CI)	P-value
Pre-induction MAP (mmHg)	0.96 (0.94 to 0.98)	< 0.001
Female sex	1.63 (1.03 to 2.57)	0.037
Use of ARBs/ACE-Is with a long half-life
vs. no regular use of ARBs/ACE-Is	4.02 (1.77 to 9.12)	< 0.001
vs. use of ARBs/ACE-Is with a short-to-middle half-life	3.17 (1.46 to 6.85)	0.003
Use of CCBs	0.44 (0.25 to 0.77)	0.004
Use of beta blockers	2.45 (1.19 to 5.04)	0.015

The odds ratios were adjusted for all explanatory variables in the multivariable logistic regression model
The explanatory variables were as follows: age; sex; body mass index; American Society of Anesthesiologists physical status; diabetes mellitus; revised cardiac risk index score > 0; ARBs/ACE-Is use, classified as no regular use, short-to-middle half-life, and long half-life; CCB use; diuretic use; beta blocker use; pre-induction MAP; propofol dose; fentanyl dose; and remifentanil dose
aOR Adjusted odds ratio, CI Confidence interval, MAP Mean arterial blood pressure, ARB Angiotensin receptor blocker, ACE-I Angiotensin-converting enzyme inhibitor, CCB Calcium channel blocker

ISSN: 1471-2253