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Table 2 Patients’ baseline and anesthesia-related characteristics

From: Predictors of hypotension during anesthesia induction in patients with hypertension on medication: a retrospective observational study

Items

All n = 395

Hypotension n = 188

Non-hypotension n = 207

P-value

Age (years)

70 [61–78]

73 [63–80]

69 [60–76]

0.017

Female sex

184 (46.6)

101 (53.7)

83 (40.1)

0.009

BMI (kg/m2)

24.5 [22.2–27.0]

24.7 [22.2–27.0]

24.5 [22.0–26.7]

0.540

ASA PS III (vs. II)

10 (2.5)

7 (3.7)

3 (1.4)

0.203

DM

101 (25.6)

53 (28.2)

48 (23.2)

0.299

RCRI > 0

99 (25.1)

52 (27.7)

47 (22.7)

0.296

Hyperlipidemia

89 (22.5)

56 (29.8)

33 (15.9)

0.001

CKD (eGFR < 60 mL/min/1.73 m2)

118 (29.9)

66 (35.1)

52 (25.1)

0.036

Heart failure

2 (0.5)

2 (1.1)

0 (0)

0.226

Ischemic heart disease

41 (10.4)

23 (12.2)

18 (8.7)

0.322

Cerebrovascular disease

52 (13.2)

24 (12.8)

28 (13.5)

0.882

Long-term medication use

 ARBs/ACE-Is

  No regular use

135 (34.2)

50 (26.6)

85 (41.1)

0.003

  Short-to-middle half-life

216 (54.7)

107 (56.9)

109 (52.7)

0.419

  Long half-life

44 (11.1)

31 (16.5)

13 (6.3)

0.001

 CCBs

299 (75.7)

128 (68.1)

171 (82.6)

0.001

 Diuretics

61 (15.4)

29 (15.4)

32 (15.5)

1.000

 Beta blockers

47 (11.9)

32 (17.0)

15 (7.2)

0.003

 Monotherapy

181 (45.8)

75 (39.9)

106 (51.2)

0.026

Pre-induction SAP (mmHg)

145 [132–159]

142 [128–158]

147 [133–160]

0.009

Pre-induction MAP (mmHg)

92 [86–102]

89 [82–97]

96 [89–106]

 < 0.001

Pre-induction DAP (mmHg)

78 [69–86]

74 [65–81]

82 [72–88]

 < 0.001

Baseline SAP (mmHg)

137 [124–148]

134 [120–145]

140 [129–151]

 < 0.001

Baseline DAP (mmHg)

80 [71–89]

76 [67–86]

83 [74–91]

 < 0.001

Propofol (mg/kg)

1.51 [1.25–1.79]

1.47 [1.21–1.74]

1.54 [1.34–1.84]

0.006

Fentanyl (µg/kg)

1.56 [1.37–1.86]

1.54 [1.26–1.87]

1.58 [1.41–1.86]

0.069

Remifentanil (µg/kg)

3.1 [2.6–3.7]

3.0 [2.4–3.5]

3.2 [2.7–3.8]

0.011

Sevoflurane (vs Desflurane)

239 (60.5)

110 (58.5)

129 (62.3)

0.471

  1. Data are presented as medians [25th–75th percentile] or numbers (percentages). For categorical data, Fisher’s exact test was used. For continuous data, the Mann–Whitney U-test was used
  2. BMI Body mass index, ASA PS American Society of Anesthesiologists physical status, DM Diabetes mellitus, RCRI Revised cardiac risk index, CKD Chronic kidney disease, eGFR Estimated glomerular filtration rate, ARB Angiotensin receptor blocker, ACE-I Angiotensin-converting enzyme inhibitor, CCB Calcium channel blocker, SAP Systolic arterial blood pressure, MAP Mean arterial blood pressure, DAP Diastolic arterial blood pressure
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BMC Anesthesiology

ISSN: 1471-2253

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