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Table 4 Analysis of adverse events

From: Sedative effect and safety of different doses of S-ketamine in combination with propofol during gastro-duodenoscopy in school-aged children: a prospective, randomized study

 

Group P (n = 30)

Group S0.3 (n = 29)

Group S0.5 (n = 30)

Group S0.7 (n = 30)

P value

After induction

 Total number of adverse events

2 (6.7%)

2 (6.9%)

3 (10.0%)

3 (10.0%)

1.000

 Akinetic state

0 (0.0%)

0 (0.0%)

0 (0.0%)

1 (3.3%)

1.000

 Hypoxemia

2 (6.7%)

2 (6.9%)

3 (10.0%)

3 (10.0%)

1.000

During the procedure

 Total number of adverse events

12 (40.0%)

12 (41.4%)

8 (26.7%)

3 (10.0%)† ‡

0.026

 Hypotension

7 (23.3%)

7 (24.1%)

1 (3.3%)† ‡

1 (3.3%)† ‡

0.01

 Coughing/hiccups

5 (16.7%)

5 (17.2%)

6 (20.0%)

2 (6.7%)

0.503

 Hypoxemia

2 (6.7%)

1 (3.4%)

1 (3.3%)

0 (0.0%)

0.753

After the procedure

 Total case of adverse events

10 (33.3%)

17 (58.6%)

18 (60.0%)

22 (73.3%)

0.016

 Dizziness

8 (26.7%)

12 (41.4%)

13 (43.3%)

22 (73.3%)

0.003

 Visual disturbance

2 (6.7%)

7 (24.1%)

7 (23.3%)

5 (16.7%)

0.276

 Headache

3 (10.0%)

1 (3.4%)

1 (3.3%)

3 (10.0%)

0.628

 Nausea/vomiting

1 (3.3%)

0 (0.0%)

0 (0.0%)

1 (3.3%)

1.000

 Fatigue

0 (0.0%)

1 (3.4%)

0 (0.0%)

0 (0.0%)

0.244

 Abdominal pain

1 (3.3%)

0 (0.0%)

1 (3.3%)

0 (0.0%)

1.000

  1. Data are expressed as n (%)
  2. P < 0.05 vs Group P; P < 0.05 vs Group S0.3