Table 3 Intraoperative maternal hemodynamics, adverse effects, and use of uterotonic agent
Variables | Glycopyrrolate group (n = 128) | Saline group (n = 127) | P |
|---|---|---|---|
Overall hypotension | 38 (30) | 49 (39) | 0.13 |
Episodes of hypotension (> 1) | 20 (16) | 28 (22) | 0.20 |
Lowest SBP (mmHg) | 99.79 ± 11.29 | 95.21 ± 11.64 | 0.001 |
Bradycardia (HR < 55/min) | 3 (2) | 7 (6) | 0.22 |
Maternal tachycardia (HR > 100/min) | 89 (70) | 73 (57) | 0.04 |
Reactive hypertension (SBP > 20% baseline) | 13 (10) | 7 (6) | 0.17 |
Nausea | 18 (14) | 23 (18) | 0.39 |
Vomiting | 9 (7) | 15 (12) | 0.20 |
Shivering | 13 (10) | 18 (14) | 0.35 |
Dry mouth | 66 (52) | 51 (40) | 0.08 |
Atropine used for bradycardia | 1 (1) | 3 (2) | 0.31 |
Pethidine used for shivering | 6 (5) | 12 (9) | 0.22 |
Oxytocin used (Units) | 6.84 ± 2.37 | 7.18 ± 2.92 | 0.49 |
Carboprost | 17 (13) | 22 (17) | 0.24 |
Methylergonovine | 6 (5) | 3 (2) | 1.00 |
Carboprost + methylergonovine | 8 (6) | 11 (9) | 0.49 |