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Table 2 Baseline characteristics of the study population

From: The efficacy and safety of an adapted opioid-free anesthesia regimen versus conventional general anesthesia in gynecological surgery for low-resource settings: a randomized pilot study

Characteristics

Total sample

N = 36 (%)

OFA group

N = 18 (%)

CGA group

N = 18 (%)

RR

95% CI

p—value

Age (mean in years)

40.3 ± 10.7

39.2 ± 12.2

41.4 ± 9.2

-

-

0.6227

Parity

3.4 ± 2.8

3.1 ± 2.8

3.8 ± 2.8

-

-

0.4233

Past history

   

-

-

0.3456

 None

32 (88.8)

15 (83.3)

17 (94.4)

   

 HIV

2 (5.6)

1 (5.6)

1 (5.6)

   

 Hypertension

2 (5.6)

2 (11.1)

0 (0)

   

Type of surgery

   

-

-

0.0555

 Myomectomy

17 (47.2)

5 (27.8)

12 (66.7)

   

 Ovarian cystectomy

8 (22.2)

7 (38.9)

1 (5.5)

   

 Hysterectomy

6 (16.7)

3 (16.7)

3 (16.7)

   

 Mastectomy

5 (13.9)

3 (16.7)

2 (11.1)

   

Surgical Indications

   

-

-

0.1811

 Mymectomy

  Fibroid – menometrorrh

13 (36.1)

6 (33.3)

7 (38.9)

   

  Fibroid – infertility

4 (11.1)

1 (5.6)

3 (16.7)

   

  Fibroid—pain

1 (2.8)

0 (0)

1 (5.6)

   

 Hysterectomy

  Localized cervical cancer

4 (11.1)

1 (5.6)

3 (16.7)

   

 Mastectomy

  Invasive ductal carcinoma

6 (16.7)

3 (16.7)

3 (16.7)

   

 Ovarian cystectomy

  Benign ovarian cyst

8 (22.2)

7 (38.9)

1 (5.6)

   

Pre-anaesthesia parameters

 Mean SBP (mmHg)

124.8 ± 12.8

122 ± 14.1

127.7 ± 11.1

-

-

0.1525

 Median SBP (mmHg)

126

119.5

126

-

-

0.1525

 Mean DBP (mmHg)

77.4 ± 10.8

76 ± 11.4

78.8 ± 10.2

-

-

0.4957

 Median DBP (mmHg)

80

78.5

81

-

-

0.4957

 Mean of MAP (mmHg)

89 ± 29.9

82.8 ± 40.9

95.3 ± 9.1

-

-

0.2168

 Median MAP (mmHg)

93.5

93

96.5

-

-

0.2168

 Mean pulse (bpm)

84.6 ± 13.4

82.9 ± 15.1

86.2 ± 11.7

-

-

0.3110

 Median pulse (bpm)

83

78.5

87

-

-

0.3110

 Mean SaO2 (%)

97.4 ± 14.9

99.8 ± 0.5

95.0 ± 21.2

-

-

0.5975

 Median SaO2 (%)

100

100

100

-

-

0.5975

Mean BMI (kg/m2)

25.7 ± 5.1

23.9 ± 5.7

27.5 ± 3.6

3.6

0.37 – 6.83

0.0080

ASA

   

0.7

0.37 – 1.33

0.2443

 I

23 (63.8)

13 (72.2)

10 (55.6)

   

 II

13 (36.1)

5 (27.8)

8 (44.4)

   
  1. ASA American Society of Anesthesiology, bpm Beats per minute, BMI Body mass index, CGA Conventional general anesthesia, CI Confidence interval, DPB Diastolic blood pressure, MAP Mean arterial pressure, menometrorrh Menometrorrhagia, OFA Opioid-free anesthesia, RR RR ratio, SaO2 Oxygen peripheral saturation, SBP Systolic blood pressure