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Table 1 The correlation between VDAC1 expression and clinicopathological characteristics in BRCA patients

From: Lidocaine promotes apoptosis in breast cancer cells by affecting VDAC1 expression

Characteristics BRCA cohort VDAC1 expression P
(n = 527) Low (n = 263) High (n = 264)
Age (median) 59 (48–67) 57 (47–65) 60 (50–68) 0.053
Gender
  Male 6 (1.1) 2 4 0.414
  Female 521 (98.9) 261 260
Pathologic stage
  i 94 (17.8) 62 32 0.001
  ii 296 (56.2) 144 152
  iii 111 (21.1) 50 61
  iv 26 (4.9) 7 19
Pathology T stage
  T1 134 (25.4) 81 53 0.027
  T2 313 (59.4) 148 165
  T3 60 (11.4) 27 33
  T4 20 (3.8) 7 13
Pathology N stage
  N0 266 (50.5) 143 123 0.198
  N1 171 (32.4) 83 88
  N2 61 (11.6) 26 35
  N3 29 (5.5) 11 18
Pathology M stage
  M0 512 (97.2) 260 252 0.019
  M1 15 (2.8) 3 12
Radiation therapy
  No 262 (49.7) 121 141 0.089
  Yes 265 (50.3) 142 123
Metastasis
  No 212 (40.2) 119 93 0.019
  Yes 315 (59.8) 144 171