Table 1 The correlation between VDAC1 expression and clinicopathological characteristics in BRCA patients
From: Lidocaine promotes apoptosis in breast cancer cells by affecting VDAC1 expression
Characteristics | BRCA cohort | VDAC1 expression | P | |
|---|---|---|---|---|
(n = 527) | Low (n = 263) | High (n = 264) | ||
Age (median) | 59 (48–67) | 57 (47–65) | 60 (50–68) | 0.053 |
Gender | ||||
Male | 6 (1.1) | 2 | 4 | 0.414 |
Female | 521 (98.9) | 261 | 260 | |
Pathologic stage | ||||
i | 94 (17.8) | 62 | 32 | 0.001 |
ii | 296 (56.2) | 144 | 152 | |
iii | 111 (21.1) | 50 | 61 | |
iv | 26 (4.9) | 7 | 19 | |
Pathology T stage | ||||
T1 | 134 (25.4) | 81 | 53 | 0.027 |
T2 | 313 (59.4) | 148 | 165 | |
T3 | 60 (11.4) | 27 | 33 | |
T4 | 20 (3.8) | 7 | 13 | |
Pathology N stage | ||||
N0 | 266 (50.5) | 143 | 123 | 0.198 |
N1 | 171 (32.4) | 83 | 88 | |
N2 | 61 (11.6) | 26 | 35 | |
N3 | 29 (5.5) | 11 | 18 | |
Pathology M stage | ||||
M0 | 512 (97.2) | 260 | 252 | 0.019 |
M1 | 15 (2.8) | 3 | 12 | |
Radiation therapy | ||||
No | 262 (49.7) | 121 | 141 | 0.089 |
Yes | 265 (50.3) | 142 | 123 | |
Metastasis | ||||
No | 212 (40.2) | 119 | 93 | 0.019 |
Yes | 315 (59.8) | 144 | 171 | |