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Fig. 4 | BMC Anesthesiology

Fig. 4

From: Fentanyl activates ovarian cancer and alleviates chemotherapy-induced toxicity via opioid receptor-dependent activation of EGFR

Fig. 4

Fentanyl reveres the pro-apoptotic effect of chemotherapeutic drugs in ovarian cancer cells. The combination of fentanyl (400 nM) with cisplatin (5 µM) or paclitaxel (100 nM) induced significantly less apoptosis than cisplatin or paclitaxel alone in SK-OV-3 (A), TOV-21G (B) and SW626 (C) cells. *, P < 0.01, compared to cisplatin or paclitaxel

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BMC Anesthesiology

ISSN: 1471-2253

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