|  | GroupD1 (n = 16) | GroupD2 (n = 18) | GroupD3 (n = 18) | GroupC (n = 17) | Pa | Pb | Pc | Pd | Pe | Pf |
---|---|---|---|---|---|---|---|---|---|---|---|
PR (ms) | T1 | 147.4 ± 17.5 | 154.7 ± 15.6 | 149.2 ± 17.9 | 149.9 ± 17.9 | 0.223 | 0.763 | 0.678 | 0.342 | 0.415 | 0.903 |
T2 | 170.6 ± 12.0 | 171.4 ± 14.5 | 158.0 ± 19.6 | 149.6 ± 19.2 | 0.878 | 0.032 | 0.001 | 0.019 |  < 0.001 | 0.141 | |
T6 | 164.6 ± 18.5 | 163.7 ± 13.4 | 161.4 ± 21.3 | 157.7 ± 20.3 | 0.888 | 0.621 | 0.290 | 0.715 | 0.343 | 0.555 | |
T7 | 161.6 ± 18.6 | 165.9 ± 17.4 | 162.1 ± 23.2 | 156.4 ± 18.1 | 0.515 | 0.942 | 0.446 | 0.552 | 0.151 | 0.390 | |
T8 | 154.9 ± 13.5 | 150.0 ± 16.1 | 152.7 ± 19.9 | 157.9 ± 16.3 | 0.393 | 0.701 | 0.608 | 0.627 | 0.165 | 0.359 | |
T9 | 147.1 ± 18.9 | 150.0 ± 13.9 | 143.8 ± 21.1 | 155.1 ± 19.5 | 0.646 | 0.614 | 0.220 | 0.322 | 0.423 | 0.078 | |
T10 | 146.1 ± 17.1 | 148.2 ± 14.1 | 141.6 ± 15.7 | 150.9 ± 19.5 | 0.707 | 0.439 | 0.403 | 0.238 | 0.631 | 0.102 | |
T11 | 145.8 ± 16.6 | 148.7 ± 15.6 | 145.6 ± 17.1 | 150.9 ± 17.3 | 0.619 | 0.964 | 0.385 | 0.577 | 0.695 | 0.348 | |
PT1-2 |  < 0.001 |  < 0.001 | 0.007 |  > 0.99 |  |  |  |  |  |  | |
PT1-6 |  < 0.001 | 0.153 | 0.007 | 0.523 |  |  |  |  |  |  | |
PT1-7 | 0.009 | 0.059 | 0.014 |  > 0.99 |  |  |  |  |  |  | |
PT1-8 | 0.801 |  > 0.99 |  > 0.99 | 0.465 |  |  |  |  |  |  | |
PT1-9 |  > 0.99 |  > 0.99 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT1-10 |  > 0.99 | 0.052 | 0.008 |  > 0.99 |  |  |  |  |  |  | |
PT1-11 |  > 0.99 | 0.696 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT2-6 |  > 0.99 | 0.160 |  > 0.99 | 0.134 |  |  |  |  |  |  | |
PT2-7 | 0.219 |  > 0.99 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT2-8 |  < 0.001 |  < 0.001 |  > 0.99 | 0.364 |  |  |  |  |  |  | |
PT2-9 |  < 0.001 |  < 0.001 |  < 0.001 |  > 0.99 |  |  |  |  |  |  | |
PT2-10 |  < 0.001 |  < 0.001 |  < 0.001 |  > 0.99 |  |  |  |  |  |  | |
PT2-11 |  < 0.001 |  < 0.001 | 0.004 |  > 0.99 |  |  |  |  |  |  | |
QRS (ms) | T1 | 88.5 ± 7.9 | 88.6 ± 10.5 | 86.2 ± 9.8 | 84.0 ± 9.4 | 0.973 | 0.477 | 0.179 | 0.973 | 0.443 | 0.156 |
T2 | 89.3 ± 10.6 | 87.7 ± 10.9 | 87.5 ± 12.1 | 84.2 ± 8.4 | 0.666 | 0.634 | 0.175 | 0.963 | 0.335 | 0.359 | |
T6 | 88.9 ± 9.7 | 87.3 ± 8.9 | 84.7 ± 10.7 | 84.5 ± 8.4 | 0.632 | 0.216 | 0.196 | 0.432 | 0.395 | 0.940 | |
T7 | 90.3 ± 9.6 | 88.7 ± 9.0 | 85.4 ± 9.5 | 85.1 ± 7.2 | 0.617 | 0.128 | 0.113 | 0.288 | 0.257 | 0.931 | |
T8 | 90.1 ± 10.5 | 88.4 ± 11.8 | 86.2 ± 9.2 | 85.4 ± 8.6 | 0.973 | 0.476 | 0.353 | 0.484 | 0.356 | 0.814 | |
T9 | 87.6 ± 7.7 | 87.7 ± 10.3 | 84.5 ± 9.2 | 84.6 ± 8.1 | 0.989 | 0.313 | 0.333 | 0.292 | 0.313 | 0.977 | |
T10 | 87.3 ± 8.5 | 87.7 ± 9.8 | 82.7 ± 7.9 | 86.6 ± 7.7 | 0.891 | 0.127 | 0.826 | 0.088 | 0.714 | 0.184 | |
T11 | 87.2 ± 6.6 | 85.9 ± 8.7 | 84.9 ± 9.8 | 85.8 ± 8.5 | 0.673 | 0.437 | 0.634 | 0.712 | 0.951 | 0.763 | |
PT1-2 |  > 0.99 |  > 0.99 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT1-6 |  > 0.99 |  > 0.99 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT1-7 |  > 0.99 |  > 0.99 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT1-8 |  > 0.99 |  > 0.99 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT1-9 |  > 0.99 |  > 0.99 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT1-10 |  > 0.99 |  > 0.99 | 0.830 |  > 0.99 |  |  |  |  |  |  | |
PT1-11 |  > 0.99 |  > 0.99 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT2-6 |  > 0.99 |  > 0.99 | 0.247 |  > 0.99 |  |  |  |  |  |  | |
PT2-7 |  > 0.99 |  > 0.99 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT2-8 |  > 0.99 |  > 0.99 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT2-9 |  > 0.99 |  > 0.99 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT2-10 |  > 0.99 |  > 0.99 | 0.061 |  > 0.99 |  |  |  |  |  |  | |
PT2-11 |  > 0.99 | 0.804 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
QTc (ms) | T1 | 413.8 ± 11.1 | 414.4 ± 12.2 | 416.2 ± 14.7 | 409.2 ± 15.5 | 0.882 | 0.605 | 0.341 | 0.703 | 0.259 | 0.134 |
T2 | 427.0 ± 11.7 | 425.2 ± 12.6 | 408.1 ± 17.3 | 410.0 ± 14.9 | 0.719 |  < 0.001 | 0.001 | 0.001 | 0.003 | 0.690 | |
T6 | 429.9 ± 9.5 | 423.8 ± 10.1 | 419.6 ± 21.0 | 424.5 ± 14.3 | 0.228 | 0.044 | 0.292 | 0.389 | 0.888 | 0.323 | |
T7 | 428.7 ± 11.0 | 419.1 ± 13.9 | 413.3 ± 15.3 | 422.2 ± 9.0 | 0.031 | 0.001 | 0.148 | 0.171 | 0.468 | 0.040 | |
T8 | 419.2 ± 9.2 | 419.0 ± 13.4 | 413.0 ± 14.7 | 422.8 ± 10.6 | 0.965 | 0.147 | 0.398 | 0.148 | 0.361 | 0.021 | |
T9 | 418.0 ± 12.5 | 411.2 ± 16.2 | 405.7 ± 14.8 | 411.4 ± 13.9 | 0.174 | 0.016 | 0.192 | 0.258 | 0.970 | 0.250 | |
T10 | 413.8 ± 8.8 | 410.1 ± 12.7 | 404.0 ± 12.9 | 410.2 ± 15.0 | 0.397 | 0.027 | 0.419 | 0.151 | 0.977 | 0.149 | |
T11 | 408.1 ± 15.0 | 411.3 ± 13.3 | 412.1 ± 17.7 | 407.4 ± 16.5 | 0.554 | 0.457 | 0.897 | 0.874 | 0.464 | 0.375 | |
PT1-2 |  < 0.001 |  < 0.001 | 0.039 |  > 0.99 |  |  |  |  |  |  | |
PT1-6 |  < 0.001 | 0.023 |  > 0.99 |  < 0.001 |  |  |  |  |  |  | |
PT1-7 |  < 0.001 |  > 0.99 |  > 0.99 | 0.002 |  |  |  |  |  |  | |
PT1-8 |  > 0.99 |  > 0.99 |  > 0.99 | 0.004 |  |  |  |  |  |  | |
PT1-9 |  > 0.99 |  > 0.99 | 0.068 |  > 0.99 |  |  |  |  |  |  | |
PT1-10 |  > 0.99 |  > 0.99 | 0.005 |  > 0.99 |  |  |  |  |  |  | |
PT1-11 |  > 0.99 |  > 0.99 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT2-6 |  > 0.99 |  > 0.99 | 0.001 |  < 0.001 |  |  |  |  |  |  | |
PT2-7 |  > 0.99 |  > 0.99 |  > 0.99 | 0.014 |  |  |  |  |  |  | |
PT2-8 |  > 0.99 |  > 0.99 |  > 0.99 | 0.025 |  |  |  |  |  |  | |
PT2-9 | 0.727 | 0.010 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT2-10 | 0.019 | 0.001 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT2-11 | 0.001 | 0.019 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
Tp-e (ms) | T1 | 84.3 ± 13.2 | 81.7 ± 8.0 | 79.6 ± 8.8 | 82.5 ± 10.3 | 0.462 | 0.183 | 0.629 | 0.535 | 0.803 | 0.390 |
T2 | 87.3 ± 14.7 | 82.1 ± 6.9 | 82.2 ± 7.7 | 81.9 ± 10.5 | 0.149 | 0.158 | 0.141 | 0.974 | 0.961 | 0.936 | |
T6 | 85.5 ± 9.6 | 83.8 ± 8.7 | 82.2 ± 9.1 | 85.9 ± 9.5 | 0.588 | 0.296 | 0.906 | 0.602 | 0.502 | 0.237 | |
T7 | 85.9 ± 8.7 | 83.4 ± 8.7 | 79.7 ± 8.0 | 84.2 ± 7.3 | 0.380 | 0.032 | 0.567 | 0.183 | 0.761 | 0.108 | |
T8 | 91.9 ± 11.0 | 87.4 ± 8.9 | 75.4 ± 10.0 | 82.5 ± 8.4 | 0.179 |  < 0.001 | 0.007 |  < 0.001 | 0.140 | 0.032 | |
T9 | 87.1 ± 11.2 | 85.3 ± 9.7 | 76.6 ± 8.8 | 81.2 ± 7.0 | 0.578 | 0.002 | 0.076 | 0.007 | 0.203 | 0.146 | |
T10 | 83.1 ± 10.8 | 82.6 ± 5.9 | 77.5 ± 7.5 | 81.9 ± 7.2 | 0.853 | 0.056 | 0.671 | 0.061 | 0.803 | 0.108 | |
T11 | 81.9 ± 9.2 | 78.9 ± 8.8 | 81.8 ± 10.1 | 80.5 ± 8.2 | 0.344 | 0.975 | 0.673 | 0.345 | 0.596 | 0.687 | |
PT1-2 |  > 0.99 |  > 0.99 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT1-6 |  > 0.99 |  > 0.99 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT1-7 |  > 0.99 |  > 0.99 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT1-8 | 0.160 | 0.733 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT1-9 |  > 0.99 |  > 0.99 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT1-10 |  > 0.99 |  > 0.99 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT1-11 |  > 0.99 |  > 0.99 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT2-6 |  > 0.99 |  > 0.99 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT2-7 |  > 0.99 |  > 0.99 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT2-8 |  > 0.99 |  > 0.99 | 0.222 |  > 0.99 |  |  |  |  |  |  | |
PT2-9 |  > 0.99 |  > 0.99 | 0.666 |  > 0.99 |  |  |  |  |  |  | |
PT2-10 |  > 0.99 |  > 0.99 | 0.358 |  > 0.99 |  |  |  |  |  |  | |
PT2-11 | 0.115 |  > 0.99 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
iCEB | T1 | 4.40 ± 0.48 | 4.51 ± 0.62 | 4.69 ± 0.69 | 4.70 ± 0.58 | 0.599 | 0.172 | 0.164 | 0.383 | 0.365 | 0.964 |
T2 | 4.85 ± 0.67 | 4.96 ± 0.69 | 4.83 ± 0.85 | 4.70 ± 0.57 | 0.666 | 0.936 | 0.537 | 0.598 | 0.284 | 0.579 | |
T6 | 4.92 ± 0.62 | 4.97 ± 0.55 | 5.13 ± 0.64 | 5.22 ± 0.55 | 0.807 | 0.312 | 0.149 | 0.428 | 0.214 | 0.641 | |
T7 | 4.81 ± 0.53 | 4.82 ± 0.51 | 4.96 ± 0.60 | 5.04 ± 0.38 | 0.962 | 0.426 | 0.219 | 0.440 | 0.223 | 0.643 | |
T8 | 4.75 ± 0.54 | 4.87 ± 0.68 | 4.48 ± 0.61 | 4.93 ± 0.46 | 0.980 | 0.047 | 0.807 | 0.043 | 0.782 | 0.024 | |
T9 | 4.59 ± 0.50 | 4.70 ± 0.64 | 4.58 ± 0.62 | 4.78 ± 0.59 | 0.587 | 0.983 | 0.364 | 0.560 | 0.701 | 0.339 | |
T10 | 4.47 ± 0.54 | 4.51 ± 0.53 | 4.73 ± 0.57 | 4.48 ± 0.44 | 0.819 | 0.160 | 0.988 | 0.224 | 0.829 | 0.158 | |
T11 | 4.57 ± 0.39 | 4.69 ± 0.51 | 4.69 ± 0.60 | 4.60 ± 0.49 | 0.503 | 0.499 | 0.866 | 0.995 | 0.611 | 0.607 | |
PT1-2 |  < 0.001 |  < 0.001 | 0.876 |  > 0.99 |  |  |  |  |  |  | |
PT1-6 |  < 0.001 |  < 0.001 |  < 0.001 |  < 0.001 |  |  |  |  |  |  | |
PT1-7 | 0.001 | 0.022 | 0.095 | 0.011 | Â | Â | Â | Â | Â | Â | |
PT1-8 |  < 0.001 | 0.010 | 0.968 | 0.624 |  |  |  |  |  |  | |
PT1-9 | 0.989 |  > 0.99 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT1-10 |  > 0.99 |  > 0.99 |  > 0.99 | 0.875 |  |  |  |  |  |  | |
PT1-11 |  > 0.99 | 0.849 |  > 0.99 |  > 0.99 |  |  |  |  |  |  | |
PT2-6 |  > 0.99 |  > 0.99 | 0.038 |  < 0.001 |  |  |  |  |  |  | |
PT2-7 |  > 0.99 |  > 0.99 |  > 0.99 | 0.044 |  |  |  |  |  |  | |
PT2-8 |  > 0.99 |  > 0.99 | 0.031 | 0.947 |  |  |  |  |  |  | |
PT2-9 | 0.317 | 0.253 | 0.319 |  > 0.99 |  |  |  |  |  |  | |
PT2-10 | 0.008 | 0.001 |  > 0.99 | 0.647 |  |  |  |  |  |  | |
PT2-11 | 0.331 | 0.304 |  > 0.99 |  > 0.99 |  |  |  |  |  |  |