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Table 5 BIS values at T0, T1, T2, T3 and T4

From: Sedative effect of remimazolam combined with alfentanil in colonoscopic polypectomy: a prospective, randomized, controlled clinical trial

Time point

AP Group

(n = 27)

AR1 Group

(n = 28)

AR2 Group

(n = 30)

AR3 Group

(n = 29)

P value

T0

96.4 ± 1.0

96.2 ± 1.4

96.4 ± 1.1

96.7 ± 1.1

P = 0.478

T1

53.9 ± 3.8

65.0 ± 2.7a

65.4 ± 2.9a

64.9 ± 3.3a

P < 0.001

T2

58.7 ± 3.5

64.8 ± 3.0a

64.6 ± 2.3a

64.0 ± 3.7a

P < 0.001

T3

55.0 ± 4.4

64.9 ± 2.9a

64.0 ± 2.4a

64.1 ± 2.3a

P < 0.001

T4

75.4 ± 8.5

78.6 ± 5.0

78.1 ± 4.7

75.0 ± 5.0b

P = 0.025

  1. Note: Data are presented as the mean ± SD
  2. Abbreviations: AP Alfentanil and propofol, AR1 Alfentanil followed by remimazolam (0.1 mg/kg), AR2 Alfentanil followed by remimazolam (0.15 mg/kg), AR3 Alfentanil followed by remimazolam (0.2 mg/kg)
  3. a P < 0.05 vs. AP group
  4. b P < 0.05 vs. AR1 group
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BMC Anesthesiology

ISSN: 1471-2253

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