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Table 5 BIS values at T0, T1, T2, T3 and T4

From: Sedative effect of remimazolam combined with alfentanil in colonoscopic polypectomy: a prospective, randomized, controlled clinical trial

Time point AP Group
(n = 27)
AR1 Group
(n = 28)
AR2 Group
(n = 30)
AR3 Group
(n = 29)
P value
T0 96.4 ± 1.0 96.2 ± 1.4 96.4 ± 1.1 96.7 ± 1.1 P = 0.478
T1 53.9 ± 3.8 65.0 ± 2.7a 65.4 ± 2.9a 64.9 ± 3.3a P < 0.001
T2 58.7 ± 3.5 64.8 ± 3.0a 64.6 ± 2.3a 64.0 ± 3.7a P < 0.001
T3 55.0 ± 4.4 64.9 ± 2.9a 64.0 ± 2.4a 64.1 ± 2.3a P < 0.001
T4 75.4 ± 8.5 78.6 ± 5.0 78.1 ± 4.7 75.0 ± 5.0b P = 0.025
  1. Note: Data are presented as the mean ± SD
  2. Abbreviations: AP Alfentanil and propofol, AR1 Alfentanil followed by remimazolam (0.1 mg/kg), AR2 Alfentanil followed by remimazolam (0.15 mg/kg), AR3 Alfentanil followed by remimazolam (0.2 mg/kg)
  3. a P < 0.05 vs. AP group
  4. b P < 0.05 vs. AR1 group