Table 4 Secondary outcomes

time of anesthesia, min

31.41 ± 9.61

32.46 ± 8.52

33.50 ± 10.33

33.66 ± 9.08

P = 0.794

time of operation, min

29.52 ± 9.71

30.39 ± 8.48

31.43 ± 10.29

31.62 ± 9.02

P = 0.823

time to full alert, min

7.44 ± 2.38

4.75 ± 1.08^a

4.63 ± 1.35^a

5.31 ± 1.54^a

P < 0.001

duration of PACU, min

5.37 ± 1.80

4.04 ± 1.48^a

3.40 ± 0.72^a

3.59 ± 0.87^a

P < 0.001

type and dose of drugs used for intraoperative anesthesia management

  alfentanil, μg

772.22 ± 151.49

805.36 ± 181.22

788.33 ± 125.33

786.21 ± 136.21

P = 0.877

  remimazolam, mg

NA

18.63 ± 3.68

19.75 ± 4.60

20.83 ± 5.33

P = 0.201

  Propofol, mg

221.11 ± 55.91

NA

NA

NA

NA

intraoperative adverse reactions

  body movement

5 (18.5%)

7 (25.0%)

2 (6.6%)

4 (13.8%)

P = 0.052

  cough

0

1 (3.6%)

0

0

P = 0.482

  hypotension

24 (88.9%)

8 (28.6%)^a

11 (36.7%)^a

10 (34.5%)^a

P < 0.001

  bradycardia

7 (25.9%)

3 (10.7%)

1 (3.3%)

2 (6.9%)

P = 0.061

postoperative adverse reactions

  pain

2 (7.4%)

1 (3.5%)

0

1 (3.4%)

P = 0.372

  nausea and vomiting

0

1 (3.5%)

0

1 (3.4%)

P = 0.735