Changes in mean systemic filling pressure as an estimate of hemodynamic response to anesthesia induction using propofol

Table 2 Hemodynamic measurements before induction, after induction, and after intubation

Parameter	Pre induction	Post induction		Post Intubation
Parameter	Median (IQR)	Median (IQR)	P_a^†	Median (IQR)	P_b^‡
HR (beats × min⁻¹)	82 (17)	77 (16)	0.004	90 (27)	0.002
MAP (mmHg)	100 (11)	78 (27)	0.001	89 (29)	0.025
CVP (mmHg)	7 (8.5)	5 (7.5)	0.590	9 (4.5)	0.026
MSFP (mmHg)	25 (7)	17 (9)	0.001	25 (9)	0.003
MSFP-CVP (mmHg)	19 (8)	12 (6)	0.001	19 (7)	0.001
CO (L × min⁻¹)	6.1 (1.6)	4.8 (2.3)	0.002	5 (2.1)	0.798
R_sys (mmHg × min × L⁻¹)	14.3 (3)	14.7 (6)	0.233	15 (4)	0.156
R_VR (mmHg × min × L⁻¹)	3.1 (2.5)	2.2 (2.2)	0.069	3.3 (1.9)	0.011
E_h	0.73 (0.24)	0.67 (0.35)	0.094	0.70 (0.19)	0.91

IQR interquartile range, HR heart rate, MAP mean arterial pressure, CVP central venous pressure, MSFP mean systemic filling pressure, P_VR pressure gradient of venous return (MSFP-CVP), CO cardiac output, R_sys systemic vascular resistance, R_VR resistance to venous return, E_h cardiac efficiency
^†P_a, Wilcoxon test between pre induction values to post induction values
^‡P_b, Wilcoxon test between post induction values to post intubation values

ISSN: 1471-2253