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Table 2 Patients characteristics and perioperative outcome variables

From: Opioid-free anesthesia compared to opioid anesthesia for laparoscopic radical colectomy with pain threshold index monitoring: a randomized controlled study

 

Group OA

n = 50

Group OFA

n = 51

StD / P

Male (n, %)

22.0 (44.0)

28.0 (54.9)

0.109¶

Age (SD)

52.5 (10.2)

53.1 (8.6)

0.058¶

Body Mass Index (BMI, SD)

24.6 (2.9)

24.4 (3.1)

0.071¶

Duration of surgery (SD, min)

196.3 (51.5)

205.1 (48.4)

0.375§

Dexmedetomidine infusion time (SD, min)

 

154.5 (37.1)

-

Remifentanil infusion time (SD, min)

192.3 (51.8)

 

-

Fluid Infusion volumes (IQR, ml)

1900.0 (1500.0.0–2445)

2000.0 (1800.0–2245.0)

0.264*

Urinary volume (IQR, ml)

550.0 (400.0–750.0)

600.0 (360.0–800.0)

0.659*

Dexmedetomidine consumption (SD, \({\varvec{\mu}}\) g)

—

125.0 (33.0)

 

Remifentanil consumption (SD, mg)

1.1 (0.4)

—

 

Atropine consumption (IQR, mg)

0.9 (0.8–1.0)

1.0 (0.8–1.1)

0.028*

Norepinephrine consumption (IQR, \({\varvec{\mu}}\) g)

28.0 (0–160.0)

6.0 (0–65.0)

0.368*

Extubation time (SD, min)

10.9 (3.6)

15.0 (6.8)

 < 0.001§

Urinary retention (n, %)

1 (2)

0

0.310#

Pruritus (n, %)

0

0

-

Postoperative nausea and vomiting (n, %)

2 (4)

0 (0)

0.149#

Bedtime (SD, h)

46.4 (11.5)

49.2 (11.1)

0.274§

Drinking time (SD, h)

46.2 (16.4)

44.4 (17)

0.593§

Time to passage of flatus (SD, h)

34.7 (18.6)

32.3 (19.9)

0.547§

Hospital discharge time (SD, day)

8.5 (2.9)

8.9 (2.8)

0.440§

Hospital expenses (SD, thousand Yuan)

80.4 (14.4)

78.6 (15.1)

0.535§

  1. Data are presented as relative number of patients, mean ± standard deviation (SD), median (IQR)
  2. ¶ Standardized differences were calculated using Cohen d (JASP); * Wilcoxon rank-sum test; # Fisher’s exact test; § unpaired Student’s t-test
  3. SD Standardized differences; Extubation time: time from the completion of intravenous neostigmine and/or nalmefene to the removal of the tracheal tube; Time to passage of flatus: the time from returning to the ward to the first breaking wind. Dexmedetomidine infusion time: the time from giving loading dose dexmedetomidine to stopping input. Remifentanil infusion time: the time from infusion remifentanil to stopping input