Fig. 2

Adjusted relative risks for the development of chronic pain. aRR Adjusted relative risk, CI Confidence interval, MMSE Minimal mental state examination, MNA Mini-nutritional assessment, HRQL Health related quality of life. Polypharmacy was added as factor with polypharmacy defined as ≥ 5 and < 10 prescriptions and excessive polypharmacy defined as ≥ 10 prescriptions used. No polypharmacy was used as reference category. Log-binomial regression was used for statistical testing with correction for EuroSCORE II, intraoperative use of remifentanil, preexisting chronic pain and use of internal mammary artery. P-value ≤ 0.01 was considered statistically significant. #; per point decrease on physical and mental HRQL