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Table 4 Hepatic blood flow & pressure measurements

From: Effect of norepinephrine infusion on hepatic blood flow and its interaction with somatostatin: an observational cohort study

Variable

Timepoint

Total Group

(n = 28)

Group S

(n = 20)

Group NS

(n = 8)

Total HBF indexed

(ml min−1 m−2)

T1

548 (182)

511 (168)

640 (191)

T2

465 (149)#

447 (153) #

508 (138)#

T3

458 (144)#

454 (145) #

467 (149)#

Relative Total HBF

(% of CO)

T1

17.8 (5.7)

16.7 (5.6)

20.4 (5.4)

T2

15.2 (4.6)#

14.7 (4.9) #

16.3 (3.8) #

T3

14.6 (4.3)#

14.6 (4.5) #

14.7 (4.0)#

HAF indexed

(ml min−1 m−2)

T1

215 (118)

216 (128)

212 (95)

T2

163 (83)#

162 (82)#

164 (92)#

T3

142 (70)#

150 (79)#

124 (41)#

Relative HAF

(% of CO)

T1

6.9 (3.6)

7.0 (3.9)

6.8 (3.0)

T2

5.3 (2.7)#

5.3 (2.5)#

5.3 (2.9)#

T3

4.6 (2.3)#

4.8 (2.6)#

3.9 (1.3)#

Conductance HAF

(ml min−1 m−2 mmHg−1)

T1

3.0 (1.8)

3.0 (1.9)

3.0 (1.4)

T2

1.9 (1.0)#

1.9 (0.9)#

2.0 (1.1)#

T2

1.6 (0.8)#

1.6 (0.9)#

1.3 (0.4)#

PVF indexed

(ml min−1 m−2)

T1

333 (137)

295 (109)*

429 (161)*

T2

302 (117)

285 (109)

344 (133)#

T3

315 (120)

304 (109)

344 (151)#

Relative PVF

(% of CO)

T1

10.9 (4.5)

9.8 (4.0)*

13.7 (4.8)*

T2

9.9 (3.7)

9.4 (2.5)

11.1 (3.8)#

T3

10.0 (3.5)

9.7 (3.3)

10.8 (4.2)#

Portal Pressure

(mmHg)

T1

10 (5)

9 (5)

11 (5)

T2

11 (5)

10 (5)

12 (5)

T3

10 (5)

9 (5)

12 (6)

Caval Pressure

(mmHg)

T1

7 (4)

6 (3)

8 (4)

T2

6 (4)

6 (4)

6 (4)

T3

7 (4)

7 (4)

6 (4)

PI Portal Vein

T1

0.6 (0.4)

0.7 (0.5)

0.5 (0.3)

T2

1.2 (2.3)

1.4 (2.7)

0.7 (0.4)

T3

0.6 (0.3)

0.6 (0.3)

0.6 (0.3)

PI Hepatic Artery

T1

1.2 (0.5)

1.3 (0.6)

1.0 (0.4)

T2

1.5 (0.5)

1.6 (0.5)

1.4 (0.5)

T3

1.5 (0.7)

1.6 (0.6)

1.4 (0.8)

  1. Data are expressed in mean (SD)
  2. HBF Hepatic Blood Flow, HAF Hepatic Arterial blood Flow, PVF Portal Vein blood Flow, PI Pulsatility Index
  3. Significant differences are marked as * for significant between group difference and # for significant within group difference, compared to T1 (p < 0.05)