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Table 3 Hospital survivors versus non-survivorsA,B

From: Methylene blue for vasodilatory shock in the intensive care unit: a retrospective, observational study

 

Survivors, n=39 (16.5%)

Non-survivors, n=197 (83.5%)

p-value

Male gender (%)

30 (76.9%)

154 (78.2%)

0.863

Age (years)

63 (14.9)

62 (15.4)

0.88

Weight (kg)

88.6 (14.2)

92.8 (26.3)

0.33

MB bolus only

25 (64.1%)

115 (58.4%)

0.51

MB bolus and infusion

14 (39.5%)

72 (36.6%)

0.94

MB bolus dose (mg/kg)

1.7 (0.42)

1.7 (0.45)

0.97

MB drip rate (mg/kg/hr)

0.39 (0.22)

0.48 (0.21)

0.15

MB drip duration (hours)

13.9 (10.9)

14.3 (12.3)

0.91

NE at 1 hours after MB (mcg/min)

34.5 (33)

61 (42)

0.0003

NE at 2 hours after MB (mcg/min)

27.7 (18.2)

57 (40.5)

<0.0001

>1 MB bolus administered (%)

7 (17.9%)

32 (16.2%)

0.79

CRRT (%)

16 (41%)

137 (69.5%)

<0.0001

IV fluids administered in first 24 hours (mL)

2352 (3096)

2951 (3186)

0.28

ICU LOS (days)

13.9 (21.9)

11.5 (21.8)

0.53

Hospital LOS (days)

28.8 (28.5)

15.3 (25.9)

0.004

SOFA Score

11.69 (2.2)

13.35 (2.9)

0.0007

  1. A Total number of patients who received MB and were assessed was 236
  2. B Data reported as mean (+/- standard deviation) unless otherwise stated with percentage symbols
  3. Abbreviations: CRRT Continuous renal replacement therapy, ICU Intensive care unit, IV Intravenous, LOS Length of stay, MB Methylene blue, NEE Norepinephrine equivalents, SOFA Sequential organ failure assessment