Table 1 Responders versus non-respondersA,B
Responders, n=88 (39.5%) | Non-Responders, n=135 (60.5%) | p-value | |
|---|---|---|---|
Male gender (%) | 60 (68.2%) | 95 (70.4%) | 0.73 |
Age (years) | 63 (13.4) | 62 (15.5) | 0.55 |
Weight (kg) | 96.2 (24.3) | 90.4 (25.1) | 0.09 |
MB bolus only (%) | 44 (50%) | 85 (63.0%) | 0.056 |
MB bolus and infusion (%) | 39 (44.3%) | 45 (33.3%) | 0.098 |
MB bolus dose (mg/kg) | 1.68 (0.49) | 1.71 (0.43) | 0.62 |
> 1 MB bolus administered (%) | 14 (15.9%) | 24 (17.8%) | 0.72 |
MB infusion rate (mg/kg/hr) | 0.48 (0.21) | 0.45 (0.21) | 0.54 |
MB infusion duration (hours) | 11.8 (9.5) | 16.7 (13.4) | 0.06 |
MAP 1 hour prior to MB (mmHg) | 61.3 (9.2) | 67 (9.3) | <0.001 |
MAP 2 hours after MB (mmHg) | 76.4 (11.1) | 61 (15.5) | <0.001 |
NE infusion rate 1 hour after MB (mcg/min) | 55 (39.1) | 54 (42) | 0.86 |
NE infusion rate 2 hours after MB (mcg/min) | 49 (30.5) | 53 (44.1) | 0.41 |
VP infusion rate 2 hours after MB (units/min) | 0.06 (0.03) | 0.05 (0.02) | 0.11 |
EPI infusion rate 2 hours after MB (mcg/min) | 6.1 (3.9) | 6.9 (5.8) | 0.36 |
Lactate 2 hours after MB (mmol/L) | 10.3 (6.1) | 9.0 (5.2) | 0.48 |
SOFA Score | 13 (2.96) | 13 (2.72) | 0.31 |
Survival to hospital discharge (%) | 19 (21.6%) | 20 (14.8%) | 0.19 |
CRRT (%) | 57 (64.8%) | 91 (67.4%) | 0.68 |
IV fluids administered in first 24 hours (mL) | 3645 (3221) | 2548 (3143) | 0.01 |