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Table 2 Multivariable logistic regression models for the prediction of postoperative AKI

From: Preoperative NT-proBNP and LVEF for the prediction of acute kidney injury after noncardiac surgery: a single-centre retrospective study

Variables

Base modela

Base model† + NT-proBNP* and LVEF

aOR (95% CI)

P value

aOR (95% CI)

P value

Age

1.005(0.989, 1.021)

0.574

0.998(0.982, 1.015)

0.813

Male sex

1.815(1.315, 2.505)

0.000

1.470(1.043, 2.071)

0.028

BMI

1.009(0.967, 1.051)

0.689

1.002(0.959, 1.046)

0.939

Medical history

 Hypertension

1.665(1.192, 2.325)

0.003

1.517(1.067, 2.157)

0.020

 Diabetes

1.279(0.910, 1.798)

0.157

1.167(0.806, 1.688)

0.414

 Coronary heart disease

1.922(1.246, 2.966)

0.003

1.689(1.052, 2.712)

0.030

 Stroke

0.914(0.525, 1.592)

0.751

0.787(0.432, 1.436)

0.435

 Congestive heart failure

3.221(2.038, 5.091)

0.000

2.401(1.436, 4.014)

0.001

 Ascites

2.571(0.760, 8.701)

0.129

2.448(0.713, 8.402)

0.155

 Use of RAAS inhibitors

1.589(1.082, 2.332)

0.018

1.603(1.066, 2.410)

0.023

Preoperative laboratory findings

 eGFR

0.997(0.992, 1.003)

0.336

0.998(0.992, 1.004)

0.513

 Proteinuria (≥ 1 +)

2.020(1.239, 3.292)

0.005

1.987(1.177, 3.355)

0.010

 Haemoglobin

0.994(0.986, 1.002)

0.146

0.997(0.989, 1.006)

0.543

 Serum albumin

1.016(0.982, 1.051)

0.365

1.024(0.987, 1.062)

0.199

Surgical characteristics

 Emergency surgery

1.582(0.799, 3.129)

0.188

1.611(0.792, 3.278)

0.188

Type of surgery

 General

  

Reference

 

 Orthopaedic

1.028(0.687, 1.538)

0.894

1.021(0.664, 1.568)

0.926

 Thoracic

0.608(0.386, 0.957)

0.032

0.592(0.366, 0.957)

0.032

 Gynaecological

1.017(0.291, 3.558)

0.979

0.841(0.225, 3.143)

0.796

 Others

2.665(0.528, 13.448)

0.235

1.338(0.214, 8.364)

0.756

 Surgery duration

1.130(1.016, 1.256)

0.024

1.154(1.032, 1.291)

0.012

 Major surgery

1.404(0.940, 2.096)

0.098

1.377(0.901, 2.103)

0.139

Type of anaesthesia

 General

1.440(0.846, 2.449)

0.179

0.648(0.368, 1.139)

0.132

ASA physical status

 I

  

Reference

 

 II

1.838(0.912, 3.707)

0.089

1.881(0.902, 3.922)

0.092

 III

3.119(1.466, 6.635)

0.003

2.564(1.155, 5.692)

0.021

 IV

5.984(2.020, 17.730)

0.001

6.124(1.858, 20.184)

0.003

ln(NT-proBNP)

  

1.269(1.101, 1.463)

0.001

LVEF

  

0.911(0.895, 0.928)

0.000

  1. Abbreviations: AKI Acute kidney injury, ASA American Society of Anesthesiologists, aOR Adjusted odds ratio, CI Confidence interval, NT-proBNP N-terminal pro-brain natriuretic peptide, LVEF Left ventricular ejection fraction
  2. * Natural log-transformed NT-proBNP
  3. aAdjusted for age (years), sex, body mass index, ASA physical status, hypertension, diabetes, coronary heart disease, stroke, congestive heart failure, ascites, the use of renin–angiotensin–aldosterone system inhibitors, emergency surgery, surgery type, surgery duration, anaesthesia type, estimated glomerular filtration rate (continuous), proteinuria, haemoglobin and serum albumin
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BMC Anesthesiology

ISSN: 1471-2253

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