Table 2 Clinical outcomes of the studied groups

Total morphine consumption (mg), mean ± SD

4.9 ± 1.2

5.8 ± 1.3

16.4 ± 3.1

0.076

 < 0.001*

 < 0.001*

Time for 1^st required analgesia (hours), mean ± SD

7.9 ± 1.2

7.5 ± 0.9

2 ± 1.2

0.24

 < 0.001*

 < 0.001*

Intraoperative fentanyl (mcg Kg^-1), mean ± SD

1.1 ± 0.2

1.1 ± 0.2

2.7 ± 0.5

0.45

 < 0.001*

 < 0.001*

Intraoperative isoflurane (ml), mean ± SD

7.9 ± 0.8

8.2 ± 0.8

13.6 ± 1.9

0.18

 < 0.001*

 < 0.001*

VAS at 1 h, median (IQR)

1 (1 -2)

1 (1–2)

2 (2 -5)

0.71

 < 0.001*

 < 0.001*

VAS at 4 h, median (IQR)

2 (1.75 – 3)

2 (2 – 3)

5 (4– 6)

0.99

 < 0.001*

 < 0.001*

VAS at 8 h, median (IQR)

4 (3 -5)

5 (4.5 -6)

6 (5 -7)

0.001*

 < 0.001*

 < 0.001*

VAS at 12 h, median (IQR)

5 (4.75 – 6)

6 (5 – 6.5)

6 (6 – 7)

0.002*

 < 0.001*

 < 0.001*

VAS at 24 h, median (IQR)

5 (4 -5)

5 (4.5 -6)

6 (5 -7)

0.44

 < 0.001*

 < 0.001*

PONV, N (%)

3 (10%)

3 (10%)

6 (20%)

–-

–-

–-